Evidence map›Paper›PMID 38404612›Full record

ArticleThe application of clinical genetics2024

Familial LCAT Deficiency and Low HDL-C Levels: In silico Characterization of Two Rare LCAT Missense Mutations.

Sebastian Ciro Acosta, Lorena Díaz-Ordóñez, Juan David Gutierrez-Medina, Yisther Katherine Silva-Cuero, Luis Guillermo Arango-Vélez, Andrés Octavio García-Trujillo, Harry Pachajoa

Open access · goldAbstract readCase Reports
In one paragraph

Article in The application of clinical genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sebastian Ciro AcostaCentro de Investigaciones en Anomalias Congenitas y Enfermedades Raras (CIACER), Universidad Icesi, Cali, Colombia.
Lorena Díaz-OrdóñezCentro de Investigaciones en Anomalias Congenitas y Enfermedades Raras (CIACER), Universidad Icesi, Cali, Colombia.ORCID 0000-0002-3140-6332
Juan David Gutierrez-MedinaCentro de Investigaciones en Anomalias Congenitas y Enfermedades Raras (CIACER), Universidad Icesi, Cali, Colombia.
Yisther Katherine Silva-CueroCentro de Investigaciones en Anomalias Congenitas y Enfermedades Raras (CIACER), Universidad Icesi, Cali, Colombia.
Luis Guillermo Arango-VélezServicio de Endocrinologia, Fundacion Valle del Lili, Cali, Colombia.
Andrés Octavio García-TrujilloServicio de Endocrinologia, Fundacion Valle del Lili, Cali, Colombia.
Harry PachajoaCentro de Investigaciones en Anomalias Congenitas y Enfermedades Raras (CIACER), Universidad Icesi, Cali, Colombia.ORCID 0000-0003-2672-0439
Fundación Valle del Lili · COIcesi University · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in the lecithin-cholesterol acyltransferase (

Indexed as

alpha-LCAT deficiencycholesterol/traffickingeyefish eye diseasegenomicsLCATLCAT deficiencylecithin cholesterol acyltransferase deficiencyVLDL

Identifiers

PMID38404612
PMCPMC10893891
OpenAlexW4391969163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.