Evidence map›Paper›PMID 38404532›Full record

ArticleContemporary clinical trials2024

A 2-arm randomized controlled study to improve the oral health of children living with HIV in Nigeria: Protocol and study design.

Yewande I Adeyemo, Muktar H Aliyu, Morenike O Folayan, Modupe O Coker, Christine A Riedy, Baba M Maiyaki, Obafunke O Denloye

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05540171 (An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05540171 nacompletednot on this map

An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.

TypeinterventionalSponsorAminu Kano Teaching HospitalRan2022 to 2023Enrolled172ConditionsHIV, Dental Caries, Quality of Life, Oral DiseaseArmsOral health education and instructions/training for self-oral care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Yewande I AdeyemoDepartment of Child Dental Health, Faculty of Dentistry, College of Health Sciences, Bayero University, Kano/Aminu Kano Teaching Hospital, Kano, Kano State. Nigeria.
Muktar H AliyuDepartment of Health Policy and Vanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Morenike O FolayanDepartment of Child Dental Health, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria.
Modupe O CokerDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ, USA.
Christine A RiedyDepartment of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Massachusetts, USA.
Baba M MaiyakiDepartment of Medicine, Bayero University, Kano/Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria.
Obafunke O DenloyeDepartment of Child Oral Health, University of Ibadan/University College Hospital, Ibadan, Oyo State, Nigeria.
Aminu Kano Teaching Hospital · NGHarvard University · USObafemi Awolowo University · NGRutgers, The State University of New Jersey · USUniversity of Ibadan · NGVanderbilt Health · US

Funding

NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
Vanderbilt-Nigeria Building Research Capacity in HIV and Non-communicable Diseases (NCDs) (V-BRCH) 2D43TW011544 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Aishatu Adamu, Muktar Hassan Aliyu · 2020 to 2026
$2.1M
FIC NIH HHS D43 TW009345FIC NIH HHS D43 TW010543
6 · The paper itself

Abstract

Background: Good oral health is an integral part of overall child health. However, immune-deficient states like the presence of Human Immunodeficiency Virus (HIV) will compromise oral health and salivary bacterial composition, leading to adverse oral conditions. Nigeria has 1.9 million HIV-positive residents, and 0.2% of incident HIV infections occur among children below 15 years. Aim: This study aims to determine through a randomized control study, the effect of an educational intervention on the oral health status and oral health-related quality of life (OHRQoL) of HIV-positive children presenting to five pediatric HIV clinics in Kano, Nigeria. Methods/Design: This 2-arm randomized control study will be conducted in five pediatric HIV outpatient clinics in Kano State, Nigeria over a period of 6 months. Eligible participants will include 172 HIV-infected frequency matched children aged 8-16 years (they can self-implement the oral health intervention with minimal supervision from the caregivers) who will be randomized and allocated into control and intervention groups. The evaluation and oral health assessment will be carried out by five examiners who will be trained and calibrated. Discussion: Our findings will help inform policies to improve the oral health and OHRQoL of HIV-positive Nigerian children and inform the need to integrate oral health care services into HIV programs in similar settings. Trial registration: ClinicalTrails.gov ID: National Clinical Trial (NCT) NCT05540171. Registered on 12

Indexed as

HIV InfectionsOral HealthChildHIVHumansNigeriaQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeHIVOral health educationOral health related quality of lifeOral health statusRandomized control study

Identifiers

PMID38404532
PMCPMC10883679
OpenAlexW4388106516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.