Evidence map›Paper›PMID 38404342›Full record

ArticleBiomedical optics express2024

Fibre-optic based exploration of lung cancer autofluorescence using spectral fluorescence lifetime.

Alexandra C Adams, András Kufcsák, Charles Lochenie, Mohsen Khadem, Ahsan R Akram, Kevin Dhaliwal, Sohan Seth

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandra C AdamsTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.ORCID https://orcid.org/0009-0004-6182-0173
András KufcsákInstitute of Photonics and Quantum Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK.ORCID https://orcid.org/0000-0002-3242-1737
Charles LochenieTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.
Mohsen KhademTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.
Ahsan R AkramTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.
Kevin DhaliwalTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.
Sohan SethTranslational Healthcare Technology Group, Institute for Regeneration and Repair, 5 Little France Dr, Edinburgh EH16 4UU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibre-optic based time-resolved fluorescence spectroscopy (TRFS) is an advanced spectroscopy technique that generates sample-specific spectral-temporal signature, characterising variations in fluorescence in real-time. As such, it can be used to interrogate tissue autofluorescence. Recent advancements in TRFS technology, including the development of devices that simultaneously measure high-resolution spectral and temporal fluorescence, paired with novel analysis methods extracting information from these multidimensional measurements effectively, provide additional insight into the underlying autofluorescence features of a sample. This study demonstrates, using both simulated data and endogenous fluorophores measured bench-side, that the shape of the

Identifiers

PMID38404342
PMCPMC10890895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.