Evidence map›Paper›PMID 38404323›Full record

ArticleBiomedical optics express2024

Multiscale imaging of corneal endothelium damage and Rho-kinase inhibitor application in mouse models of acute ocular hypertension.

Zhen Cai, Yang Zhang, Raymond S Fang, Benjamin Brenner, Junghun Kweon, Cheng Sun, Jeffrey L Goldberg, Hao F Zhang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Zhen CaiDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Yang ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Raymond S FangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID https://orcid.org/0000-0002-0647-8537
Benjamin BrennerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID https://orcid.org/0000-0003-4736-1789
Junghun KweonDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
Cheng SunDepartment of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
Jeffrey L GoldbergSpencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA 94303, USA.
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID https://orcid.org/0000-0001-5089-1196
Northwestern University · USStanford University · US

Funding

Technology Development UnitU54CA268084 · NCI · NORTHWESTERN UNIVERSITY · PI Vadim Backman · 2022 to 2026
$10.0M
Clinical glaucoma management enabled by visible-light OCTU01EY033001 · NEI · NORTHWESTERN UNIVERSITY · PI SCHUMAN, JOEL S, ZHANG, HAO F · 2021 to 2025
$3.2M
Novel ocular imaging and molecular analysis of anterior eye segment for glaucomaR01EY034740 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Tsutomu Kume, Hao F Zhang · 2023 to 2026
$2.7M
Subcellular calcium signaling in ferret visual cortical astrocytesR01EY026977 · NEI · MAX PLANCK FLORIDA CORPORATION · PI SCHUMMERS, JAMES · 2016 to 2020
$2.1M
Investigating nanoscale neuronal damages in early glaucoma towards clinical optical detectionR01EY029121 · NEI · NORTHWESTERN UNIVERSITY · PI LIU, XIAORONG, ZHANG, HAO F · 2018 to 2021
$2.0M
Physical Genomics and Engineering Training ProgramT32GM142604 · NIGMS · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2021 to 2025
$1.9M
Photoactivatable Fluorophores for High-Throughput Multiplexed Tracking of Single-Molecules in Live CellsR01GM143397 · NIGMS · UNIVERSITY OF MIAMI CORAL GABLES · PI RAYMO, FRANCISCO M · 2022 to 2025
$1.4M
Intrinsic-contrast super-resolution imaging of DNA at 2-nm resolutionR01GM139151 · NIGMS · NORTHWESTERN UNIVERSITY · PI ZHANG, HAO F · 2020 to 2023
$1.3M
Development of spectroscopic Single-Molecule Localization MicroscopyR01GM140478 · NIGMS · NORTHWESTERN UNIVERSITY · PI SUN, CHENG, ZHANG, HAO F · 2021 to 2024
$1.2M
Bright and switchable fluorophores for highly multiplexed super-resolution microscopy towards molecular interaction imagingR21GM141675 · NIGMS · NORTHWESTERN UNIVERSITY · PI ZHANG, YANG · 2021 to 2022
$400k
Anatomical and functional imaging of the conventional outflow pathwayF30EY034033 · NEI · NORTHWESTERN UNIVERSITY · PI FANG, RAYMOND · 2023 to 2024
$97k
NCI NIH HHS U54 CA268084NEI NIH HHS F30 EY034033NEI NIH HHS R01 EY026977NEI NIH HHS R01 EY029121NEI NIH HHS R01 EY034740NEI NIH HHS U01 EY033001NIGMS NIH HHS R01 GM139151NIGMS NIH HHS R01 GM140478NIGMS NIH HHS R01 GM143397NIGMS NIH HHS R21 GM141675NIGMS NIH HHS T32 GM142604
6 · The paper itself

Abstract

We developed a multiscale optical imaging workflow, integrating and correlating visible-light optical coherence tomography, confocal laser scanning microscopy, and single-molecule localization microscopy to investigate mouse cornea damage from the

Identifiers

PMID38404323
PMCPMC10890882
OpenAlexW4390945945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.