Evidence map›Paper›PMID 38404311›Full record

ArticleBiomedical optics express2024

Real-time line-field optical coherence tomography for cellular resolution imaging of biological tissue.

Kai Neuhaus, Shanjida Khan, Omkar Thaware, Shuibin Ni, Mini Aga, Yali Jia, Travis Redd, Siyu Chen, David Huang, Yifan Jian

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kai NeuhausCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0003-0779-0212
Shanjida KhanCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0002-0068-5842
Omkar ThawareCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.
Shuibin NiCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0003-3146-5006
Mini AgaCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.
Yali JiaCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0002-2784-1905
Travis ReddCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.
Siyu ChenCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0003-0336-3627
David HuangCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.ORCID https://orcid.org/0000-0003-2592-8393
Yifan JianCasey Eye Institute, Oregon Health & Science University , Portland, OR 97239, USA.
Oregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
OCTA Precursors of Vision-Threatening Complications of Diabetic RetinopathyR01EY035410 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Thomas Hwang, Yali Jia · 2023 to 2026
$2.5M
Translational Vision Science Research at Oregon Health & Science UniversityT32EY023211 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Yali Jia, Kate E Keller · 2013 to 2026
$2.4M
Advancing visible-light OCT in oxygen-induced retinopathyR01EY036429 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell, Yali Jia · 2024 to 2026
$2.0M
Visible-light OCT angiography, velocimetry, and oximetry for characterizing retinal vascular alterations in glaucomaR01EY031394 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, MORRISON, JOHN C · 2020 to 2022
$1.6M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY024544NEI NIH HHS R01 EY031394NEI NIH HHS R01 EY035410NEI NIH HHS R01 EY036429NEI NIH HHS T32 EY023211
6 · The paper itself

Abstract

A real-time line-field optical coherence tomography (LF-OCT) system is demonstrated with image acquisition rates of up to 5000 B-frames or 2.5 million A-lines per second for 500 A-lines per B-frame. The system uses a high-speed low-cost camera to achieve continuous data transfer rates required for real-time imaging, allowing the evaluation of future applications in clinical or intraoperative environments. The light source is an 840 nm super-luminescent diode. Leveraging parallel computing with GPU and high speed CoaXPress data transfer interface, we were able to acquire, process, and display OCT data with low latency. The studied system uses anamorphic beam shaping in the detector arm, optimizing the field of view and sensitivity for imaging biological tissue at cellular resolution. The lateral and axial resolution measured in air were 1.7 µm and 6.3 µm, respectively. Experimental results demonstrate real-time inspection of the trabecular meshwork and Schlemm's canal on

Identifiers

PMID38404311
PMCPMC10890841
OpenAlexW4390975316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.