ArticleBiomedical optics express2024
Laser speckle imaging of the hippocampus.
Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Laser speckle contrast imaging of hepatic microcirculation.Biomedical optics express · 2025Article
- Full-field amplitude speckle decorrelation angiography.Biomedical optics express · 2024Article
- Dynamic Light Scattering in Biomedical Applications: feature issue introduction.Biomedical optics express · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
Research on hippocampal blood flow is essential for gaining insight into its involvement in learning and memory and its role in age-related cognitive impairment and dementia. In this study, we applied laser speckle contrast imaging (LSCI) and dynamic light scattering imaging (DLSI) to monitor perfusion in mouse hippocampus via a chronic, optically transparent window. LSCI scans showed hippocampal blood vessels appear more out of focus than similar caliber vessels in the mouse cortex. We hypothesize that it is caused by the inverse vascular topology and increased contribution of multiply-scattered photons detected from the upper layers of the hippocampus. We support the hypothesis with DLSI, showing a 1300% increased contribution of multiple-scattering unordered dynamics regime in large hippocampal vessels.
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Registered trials
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