Evidence map›Paper›PMID 38404226›Full record

ArticleObstetrics & gynecology science2024

The timing of adenomyosis diagnosis and its impact on pregnancy outcomes: a national population-based study.

Young Mi Jung, Wonyoung Wi, Hwa Seon Koo, Seung-Hyuk Shim, Soo-Young Oh, Seung Mi Lee, Jin Hoon Chung, SiHyun Cho, Hyunjin Cho, Min-Jeong Oh and 2 more

Abstract read
In one paragraph

Article in Obstetrics & gynecology science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Outcome of pregnancy after adenomyomectomy: a review.Obstetrics & gynecology science · 2026
    Review
  3. Cauda equina syndrome following vaginal delivery.Obstetrics & gynecology science · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Young Mi JungDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Seoul, Korea.
Wonyoung WiDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Seoul, Korea.
Hwa Seon KooBest of ME Fertility Clinic, Department of Obstetrics and Gynecology, Seoul, Korea.
Seung-Hyuk ShimResearch Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.
Soo-Young OhSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Seung Mi LeeSeoul National University College of Medicine, Seoul, Korea.
Jin Hoon ChungDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Department of Obstetrics and Gynecology, Seoul, Korea.
SiHyun ChoGangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Hyunjin ChoHaeundae Paik Hospital, Inje University, Busan, Korea.
Min-Jeong OhDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Seoul, Korea.
Geum Joon ChoDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Seoul, Korea.
Hye-Sung WonAsan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdenomyosis impacts pregnancy outcomes, although there is a lack of consensus regarding the actual effects. It is likely, however, that the severity of adenomyosis or ultrasound findings or timing of diagnosis can have different effects on adverse pregnancy outcomes (APOs).

methodsIn this study, we aimed to investigate the impact of the timing of adenomyosis diagnosis on pregnancy outcomes. Singleton pregnant women who delivered between 2017 and 2022 were analyzed based on the timing of adenomyosis diagnosis, using a national database. The final cohort was classified into three groups: 1) group 1, without adenomyosis; 2) group 2, those diagnosed with adenomyosis before pregnancy; and 3) group 3, those diagnosed with adenomyosis during pregnancy.

resultsA total of 1,226,475 cases were ultimately included in this study. Women with a diagnosis of adenomyosis had a significantly higher risk of APOs including hypertensive disorder during pregnancy (HDP), gestational diabetes mellitus (GDM), postpartum hemorrhage, placental abruption, preterm birth, and delivery of a small-for-gestational-age infant even after adjusting for covariates. In particular, concerning HDP, the risk was highest in group 3 (group 2: adjusted odds ratio [aOR], 1.15 vs. group 3: aOR, 1.36). However, the highest GDM risk was in group 2 (GDM; group 2: aOR, 1.24 vs. group 3: aOR, 1.04).

conclusionThe increased risk of APO differed depending on the timing of adenomyosis diagnosis. Therefore, efforts for more careful monitoring and prevention of APOs may be necessary when such women become pregnant.

Indexed as

AdenomyosisGestational diabetesPreeclampsiaPregnancy outcomePreterm birth

Identifiers

PMID38404226
PMCPMC11099096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.