Evidence map›Paper›PMID 38403976›Full record

ArticleVeterinary medicine and science2024

Immune-mediated polyarthritis and anterior uveitis secondary to zonisamide administration in a dog with refractory epilepsy.

Paula Baya, Saya Press, Stephanie Istvan, Kaila Rizzo

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary medicine and science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paula BayaDepartment of Emergency and Critical Care, Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, San Diego, California, USA.ORCID 0009-0007-1200-2803
Saya PressDepartment of Emergency and Critical Care, Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, San Diego, California, USA.
Stephanie IstvanDepartment of Emergency and Critical Care, Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, San Diego, California, USA.
Kaila RizzoDepartment of Emergency and Critical Care, Veterinary Specialty Hospital of San Diego, Ethos Veterinary Health, San Diego, California, USA.
San Diego Association of Governments · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this article is to describe a case of suspected zonisamide-induced immune-mediated polyarthritis (IMPA) and anterior uveitis in a dog. A 7-year-old male neutered Siberian Husky with a history of refractory idiopathic epilepsy was presented for cluster seizures. Following the addition of zonisamide to the antiepileptic regime, the dog developed new IMPA and anterior uveitis. Within a few weeks of discontinuation of the zonisamide, the dog's IMPA and anterior uveitis resolved. These immune-mediated conditions were thus presumed to be an idiosyncratic reaction to zonisamide. To our knowledge, this is the first report of IMPA and anterior uveitis in dogs associated with zonisamide administration at its recommended dose.

Indexed as

ArthritisDog DiseasesDrug Resistant EpilepsyOrganophosphorus CompoundsUveitis, AnteriorAnimalsDogsIsoxazolesMaleZonisamideisopropyl methylphosphonic acidIsoxazolesOrganophosphorus CompoundsZonisamideadverse reactionsepilepsypolyarthritisuveitiszonisamide

Identifiers

PMID38403976
PMCPMC10895151
OpenAlexW4392161778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.