Evidence map›Paper›PMID 38403767›Full record

ReviewInternal medicine (Tokyo, Japan)2024

An Extremely Delayed Onset of Frey Syndrome: A Case Report and Literature Review.

Yuya Kobayashi, Kazuki Kasuga, Yusaku Shimizu, Yoshiki Sekijima

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuya KobayashiDepartment of Neurology, Ina Central Hospital, Japan.
Kazuki KasugaDepartment of Neurology, Ina Central Hospital, Japan.
Yusaku ShimizuDepartment of Neurology, Ina Central Hospital, Japan.
Yoshiki SekijimaDepartment of Medicine (Neurology & Rheumatology), Shinshu University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of an 80-year-old man with Frey syndrome that developed 30 years postoperatively, which is an exceptionally long period before its occurrence. Sweating and flushing occurred on only the side of his face where the surgery was performed, and he had no other causative abnormalities. Following treatment with botulinum toxin, the patient's symptoms resolved. Extremely early- and late-onset cases do not fit the conventional paradigm of this pathology. Various surgical methods to prevent this syndrome have been explored, but complete prevention has not yet been achieved. These findings suggest that the underlying pathophysiology of Frey syndrome may be more complex than previously recognized.

Indexed as

Sweating, GustatoryAged, 80 and overBotulinum Toxins, Type AHumansMalePostoperative ComplicationsTime FactorsBotulinum Toxins, Type Adelayed onsetFrey syndromegustatory sweatingparotid gland surgerypostoperative complications

Identifiers

PMID38403767
PMCPMC11518594

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.