Evidence map›Paper›PMID 38403720›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2024

Measuring EQ-5D-5L utility values in parents who have experienced perinatal death.

Elizabeth M Camacho, Katherine J Gold, Margaret Murphy, Claire Storey, Alexander E P Heazell

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions to Improve Outcomes After Pregnancy Loss: A Systematic Review.BJOG : an international journal of obstetrics and gynaecology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth M CamachoInstitute of Population Health, University of Liverpool, Liverpool, UK. elizabeth.camacho@liverpool.ac.uk.ORCID http://orcid.org/0000-0001-9574-7710
Katherine J GoldDepartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Margaret MurphySchool of Nursing and Midwifery, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0001-9979-9462
Claire StoreyTommy's Stillbirth Research Centre, University of Manchester, Manchester, UK.
Alexander E P HeazellMaternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-4303-7845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolicymakers use clinical and cost-effectiveness evidence to support decisions about health service commissioning. In England, the National Institute for Health and Care Excellence (NICE) recommend that in cost-effectiveness analyses "effectiveness" is measured as quality-adjusted life years (QALYs), derived from health utility values. The impact of perinatal death (stillbirth/neonatal death) on parents' health utility is currently unknown. This knowledge would improve the robustness of cost-effectiveness evidence for policymakers.

objectiveThis study aimed to estimate the impact of perinatal death on parents' health utility.

methodsAn online survey conducted with mothers and fathers in England who experienced a perinatal death. Participants reported how long ago their baby died and whether they/their partner subsequently became pregnant again. They were asked to rate their health on the EQ-5D-5L instrument (generic health measure). EQ-5D-5L responses were used to calculate health utility values. These were compared with age-matched values for the general population to estimate a utility shortfall (i.e. health loss) associated with perinatal death.

resultsThere were 256 survey respondents with a median age of 40 years (IQR 26-40). Median time since death was 27 months (IQR 8-71). The mean utility value of the sample was 0.774 (95% CI 0.752-0.796). Utility values in the sample were 13% lower than general population values (p < 0.05). Over 10 years, this equated to a loss of 1.1 QALYs. This reduction in health utility was driven by anxiety and depression.

conclusionsPerinatal death has important and long-lasting health impacts on parents. Mental health support following perinatal bereavement is especially important.

Indexed as

Perinatal DeathQuality-Adjusted Life YearsAdultCost-Benefit AnalysisEnglandFemaleHealth StatusHumansInfant, NewbornMaleParentsPregnancyQuality of LifeSurveys and QuestionnairesEQ-5DFoetal deathHealth utility valuesNeonatal deathStillbirth

Identifiers

PMID38403720
PMCPMC11442506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.