Evidence map›Paper›PMID 38403642›Full record

ArticleLight, science & applications2024

Light-controlled soft bio-microrobot.

Jianyun Xiong, Xing Li, Ziyi He, Yang Shi, Ting Pan, Guoshuai Zhu, Dengyun Lu, Hongbao Xin

Open access · goldAbstract read
In one paragraph

Article in Light, science & applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Phototaxis and Motility ofMicromachines · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Additive-Free TiAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Light-driven micro/nanobots.Nanophotonics (Berlin, Germany) · 2025
    Review
  13. Soft Microbot Traction on Structured Surfaces.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Jianyun Xiong *Guangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Xing Li *Guangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Ziyi HeGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Yang ShiGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.ORCID http://orcid.org/0000-0002-3336-4826
Ting PanGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Guoshuai ZhuGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Dengyun LuGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China.
Hongbao XinGuangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, Jinan University, 511443, Guangzhou, China. hongbaoxin@jnu.edu.cn.ORCID http://orcid.org/0000-0001-7132-0835
Jinan University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 12204196National Natural Science Foundation of China (National Science Foundation of China) 32271405National Natural Science Foundation of China (National Science Foundation of China) 61975065
6 · The paper itself

Abstract

Micro/nanorobots hold exciting prospects for biomedical and even clinical applications due to their small size and high controllability. However, it is still a big challenge to maneuver micro/nanorobots into narrow spaces with high deformability and adaptability to perform complicated biomedical tasks. Here, we report a light-controlled soft bio-microrobots (called "Ebot") based on Euglena gracilis that are capable of performing multiple tasks in narrow microenvironments including intestinal mucosa with high controllability, deformability and adaptability. The motion of the Ebot can be precisely navigated via light-controlled polygonal flagellum beating. Moreover, the Ebot shows highly controlled deformability with different light illumination duration, which allows it to pass through narrow and curved microchannels with high adaptability. With these features, Ebots are able to execute multiple tasks, such as targeted drug delivery, selective removal of diseased cells in intestinal mucosa, as well as photodynamic therapy. This light-controlled Ebot provides a new bio-microrobotic tool, with many new possibilities for biomedical task execution in narrow and complicated spaces where conventional tools are difficult to access due to the lack of deformability and bio-adaptability.

Identifiers

PMID38403642
PMCPMC10894875
OpenAlexW4392159001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.