Evidence map›Paper›PMID 38402518›Full record

ArticleThe British journal of radiology2024

Let us settle the controversy-gelfoam is a safe intravascular embolic agent.

Warren Clements, Matthew Lukies, Adil Zia, Mark Fitzgerald, Helen Kavnoudias

Open access · hybridAbstract read
In one paragraph

Article in The British journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Pelvic Trauma: Anatomy and Interventions.Seminars in interventional radiology · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Warren ClementsDepartment of Radiology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0003-1859-5850
Matthew LukiesDepartment of Radiology, Alfred Health, Melbourne 3004, Australia.
Adil ZiaDepartment of Radiology, Alfred Health, Melbourne 3004, Australia.
Mark FitzgeraldDepartment of Surgery, Central Clinical School, Monash University, Melbourne 3004, Australia.
Helen KavnoudiasDepartment of Radiology, Alfred Health, Melbourne 3004, Australia.
Alfred Health · AUNational Trauma Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA 2021 safety alert restricted endovascular gelfoam use in Australia and resulted in an embargo on gelfoam sales to Interventional Radiology departments. This study aimed to show that gelfoam is safe in a population of trauma patients with pelvic injury, and discuss the basis of the recent controversies.

methodsRetrospective cohort study was conducted between 1 January 2010 and 21 May 2021 for the patients who underwent gelfoam embolization for pelvic arterial haemorrhage. Primary outcome was the rate of adverse events related to intravascular gelfoam administration.

resultsInclusion criteria met in 50 patients, comprising 58% males median age 59.9 years, and median injury severity score 31. There were 0 complications related to gelfoam use and 100% technical success. Thirty-five patients (70%) received a non-targeted embolization approach. All-cause mortality was observed in 5 patients (10%), unrelated to gelfoam.

conclusionsGelfoam is a safe and effective embolic agent in pelvic trauma. Patients are in urgent need of universal on-label registration of endovascular gelfoam products, as it is life-saving in major haemorrhage after trauma. ADVANCES IN KNOWLEDGE: Endovascular gelfoam is mandatory for a high-quality trauma service, and this study shows that it is safe to use intentionally in the endovascular space. Companies should work with interventional radiologists, sharing and collaborating to ensure positive outcomes for patients.

Indexed as

Embolization, TherapeuticGelatin Sponge, AbsorbableHemorrhageAdultAgedAged, 80 and overAustraliaFemaleHemostaticsHumansInjury Severity ScoreMaleMiddle AgedPelvisRetrospective StudiesTreatment OutcomeHemostaticsfracturepelvistrauma

Identifiers

PMID38402518
PMCPMC11075981
OpenAlexW4392143516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.