Evidence map›Paper›PMID 38402406›Full record

ArticleJournal of hospital medicine2024

Vulnerability to functional decline is associated with noncardiovascular cause of 90-day readmission in hospitalized patients with heart failure.

Ricardo J Trochez, Jennifer B Barrett, Yaping Shi, Jonathan S Schildcrout, Chelsea Rick, Devika Nair, Sarah A Welch, Anupam A Kumar, Susan P Bell, Sunil Kripalani

Open access · greenAbstract read
In one paragraph

Article in Journal of hospital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ricardo J TrochezCenter for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-8567-7480
Jennifer B BarrettCenter for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Yaping ShiDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jonathan S SchildcroutDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Chelsea RickDepartment of Medicine, Division of Geriatric Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Devika NairDepartment of Medicine, Division of Nephrology & Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-7164-715X
Sarah A WelchDepartment of Physical Medicine & Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Anupam A KumarDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Susan P BellDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sunil KripalaniCenter for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-4214-7129
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US

Funding

Health Literacy, Hospital Discharge, and Cardiovascular OutcomesR01HL109388 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KRIPALANI, SUNIL · 2011 to 2015
$3.3M
Activation for Self-Care Needs in Older Adults with Chronic Kidney Disease: ACTIVE SENIORS with CKDK23DK129774 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NAIR, DEVIKA · 2022 to 2023
$351k
CSRD VA IK2 CX002595NHLBI NIH HHS 1K23 DK1297742NHLBI NIH HHS R01 HL109388NIDDK NIH HHS K23 DK129774
6 · The paper itself

Abstract

backgroundHospital readmission is common among patients with heart failure. Vulnerability to decline in physical function may increase the risk of noncardiovascular readmission for these patients, but the association between vulnerability and the cause of unplanned readmission is poorly understood, inhibiting the development of effective interventions.

objectivesWe examined the association of vulnerability with the cause of readmission (cardiovascular vs. noncardiovascular) among hospitalized patients with acute decompensated heart failure. DESIGNS, SETTINGS, AND

participantsThis prospective longitudinal study is part of the Vanderbilt Inpatient Cohort Study. MAIN OUTCOME AND MEASURES: The primary outcome was the cause of unplanned readmission (cardiovascular vs. noncardiovascular). The primary independent variable was vulnerability, measured using the Vulnerable Elders Survey (VES-13).

resultsAmong 804 hospitalized patients with acute decompensated heart failure, 315 (39.2%) experienced an unplanned readmission within 90 days of discharge. In a multinomial logistic model with no readmission as the reference category, higher vulnerability was associated with readmission for noncardiovascular causes (relative risk ratio [RRR] = 1.36, 95% confidence interval [CI]: 1.06-1.75) in the first 90 days after discharge. The VES-13 score was not associated with readmission for cardiovascular causes (RRR = 0.94, 95% CI: 0.75-1.17).

conclusionsVulnerability to functional decline predicted noncardiovascular readmission risk among hospitalized patients with heart failure. The VES-13 is a brief, validated, and freely available tool that should be considered in planning care transitions. Additional work is needed to examine the efficacy of interventions to monitor and mitigate noncardiovascular concerns among vulnerable patients with heart failure being discharged from the hospital.

Indexed as

Heart FailurePatient ReadmissionAgedAged, 80 and overFemaleHospitalizationHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID38402406
PMCPMC11824873
OpenAlexW4392136640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.