Evidence map›Paper›PMID 38402160›Full record

ArticleAnnals of clinical microbiology and antimicrobials2024

Characterization of resistance genes and replicon typing in Carbapenem-resistant Klebsiella pneumoniae strains.

Esin Karaman, Ayşegül Çopur Çiçek, Vicdan Şemen, Fatih Şaban Beriş

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Esin KaramanFaculty of Arts&Sciences, Department of Biology, Recep Tayyip Erdogan University, Rize, Turkey.ORCID http://orcid.org/0000-0001-6767-3419
Ayşegül Çopur ÇiçekFaculty of Medicine, Department of Medical Microbiology, İstanbul Medipol University, İstanbul, Turkey.ORCID http://orcid.org/0000-0002-3673-9670
Vicdan ŞemenDepartment of Microbiology, Sakarya Yenikent State Hospital, Sakarya, Turkey.ORCID http://orcid.org/0000-0002-1540-7968
Fatih Şaban BerişFaculty of Arts&Sciences, Department of Biology, Recep Tayyip Erdogan University, Rize, Turkey. fatihberis@gmail.com.ORCID http://orcid.org/0000-0002-0535-943X
Recep Tayyip Erdoğan University · TRIstanbul Medipol University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn our study, K. pneumoniae strains (non-susceptible to carbapenem) (n = 60) were obtained from various clinical samples from Rize State Hospital between 2015 and 2017 and it is aimed to identify antibiotic resistance genes and replicon typing.

methodsAntibiotic susceptibility tests of the strains were performed with Kirby-Bauer disk diffusion test and the Vitek-2 automated system (BioMerieux, France). Antibiotic resistance genes and replicon typing was characterized by PCR method.

resultsIt was determined that K. pneumaniae isolates were mostly isolated from the samples of the intensive care unit. All of the K. pneumoniae strains examined in this study were found to be ampicillin/sulbactam and ertapenem resistant but colistin susceptible. Amoxacillin/clavulonic acid resistance was detected at 98.14% of strains. The bla

conclusionThis study also shows that the distribution of NDM-1 and OXA-48 carbapenemases has increased since the first co-display in Türkiye and that IncHI1 is the first record in our country. This study provides an overview of the major plasmid families occurring in multiple antibiotic-resistant strains of K. pneumoniae. To our knowledge, this study represents the first report of IncHI1 record in Türkiye.

Indexed as

Carbapenem-Resistant EnterobacteriaceaeKlebsiella InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsRepliconAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsAntibiotic resistance genesAntibiotic susceptibilityCarbapenem resistanceK. pneumoniaeReplicon typing

Identifiers

PMID38402160
PMCPMC10893597
OpenAlexW4392131271

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.