Evidence map›Paper›PMID 38401901›Full record

ArticleBMJ open2024

Effects of immersive virtual reality for alleviating anxiety, nausea and vomiting among patients with paediatric cancer receiving their first chemotherapy: protocol for a randomised controlled trial.

Cho Lee Wong, Huiyuan Li, Chi Kong Li, Carmen Wing Han Chan, Yin Ting Cheung, Kai Chow Choi, Winnie Kwok Wei So

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cho Lee Wong *The Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China jojowong@cuhk.edu.hk.ORCID 0000-0001-6640-1323
Huiyuan Li *The Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0002-0207-691X
Chi Kong LiDeparment of Paediatrics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.ORCID 0000-0002-2810-5758
Carmen Wing Han ChanThe Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Yin Ting CheungSchool of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Kai Chow ChoiThe Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Winnie Kwok Wei SoThe Nethersole School of Nursing, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Chinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnxiety, nausea and vomiting are common side effects suffered by paediatric patients receiving chemotherapy. Emerging evidence supports the efficacy of immersive virtual reality (IVR) on improving anxiety and distress symptoms including nausea and vomiting in this vulnerable group. This trial aims to evaluate the effects of IVR intervention on anxiety, chemotherapy-induced nausea and vomiting and anticipatory nausea and vomiting in patients with paediatric cancer receiving first chemotherapy. METHOD AND ANALYSIS: An assessor-blinded, randomised controlled trial with a mixed methods evaluation approach. On the basis of our pilot results, 128 chemotherapy-naive patients with paediatric cancer scheduled to receive their first intravenous chemotherapy will be recruited from a public hospital and randomly allocated to intervention (n=64) or control groups (n=64). The intervention group will receive the IVR intervention for three sessions: 2 hours before the first chemotherapy, 5 min before and during their first chemotherapy and 5 min before and during their second chemotherapy, respectively. The control group will receive standard care only. A subsample of 30 participants in the intervention group will be invited for a qualitative interview. Study instruments are: (1) short form of the Chinese version of the State Anxiety Scale for Children, (2) visual analogue scale for anticipatory nausea and vomiting, (3) Chinese version of the Multinational Association of Supportive Care in Cancer Antiemesis Tool and (4) individual face-to-face semistructured interviews to explore intervention participants' perceptions of the IVR intervention. ETHICS AND DISSEMINATION: This study has been approved by the Hong Kong Children's Hospital Research Ethics Committee (HKCH-REC-2021-009). The findings will be disseminated in peer-reviewed journals and through local or interventional conference presentations. TRIAL REGISTRATION NUMBER: ChiCTR2100048732.

Indexed as

NeoplasmsVomitingAnxietyAnxiety DisordersChildHumansNauseaRandomized Controlled Trials as TopicCHEMOTHERAPYNursing CarePaediatric oncologyVirtual Reality

Identifiers

PMID38401901
PMCPMC10895243
OpenAlexW4392131485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.