SynthesisValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2024
Economic Evaluations of Establishing Opioid Overdose Prevention Centers in 12 North American Cities: A Systematic Review.
Synthesis in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cost-effective interventions to prevent prescription drug misuse: a systematic review.Frontiers in public health · 2025Pooled it
- County by county estimation of possible deaths averted, infections averted, and cost savings of overdose prevention centers in the United States from July 2019-June 2025.The International journal on drug policy · 2026Article
- "Once I started going… I had this central wheel hub": Drivers of overdose prevention center engagement and connections to care in Rhode Island.The International journal on drug policy · 2026Article
- A community-based systematic review of economic evaluations of overdose prevention sites for people who use drugs: a study protocol.Substance abuse treatment, prevention, and policy · 2026Article
- County by county estimation of possible deaths averted, infections averted, and cost savings of overdose prevention centers in the United States from July 2019-June 2025.medRxiv : the preprint server for health sciences · 2026Article
- Overdose Prevention Centers and Neighborhood Commercial Activity in New York City.JAMA network open · 2026Article
- Saskatoon, Saskatchewan's safe consumption site provides a sizeable social and economic return on investment.Frontiers in public health · 2026Article
- An Examination of How People Who Use Drugs Conceptualize the Benefits and Drawbacks of Using Overdose Prevention Centers.Contemporary drug problems · 2025Article
- Study assessing the effectiveness of overdose prevention centers through research (SAFER): an overview of the study protocol.Harm reduction journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesOverdose prevention centers (OPCs) provide a safe place where people can consume preobtained drugs under supervision so that a life-saving medical response can be provided quickly in the event of an overdose. OPCs are programs that are established in Canada and have recently become legally sanctioned in only a few United States jurisdictions.
methodsWe conducted a systematic review that summarizes and identifies gaps of economic evidence on establishing OPCs in North America to guide future expansion of OPCs.
resultsWe included 16 final studies that were evaluated with the Consolidated Health Economic Evaluation Reporting Standards and Drummond checklists. Eight studies reported cost-effectiveness results (eg, cost per overdose avoided or cost per quality-adjusted life-year), with 6 also including cost-benefit; 5 reported only cost-benefit results, and 3 cost offsets. Health outcomes primarily included overdose mortality outcomes or HIV/hepatitis C virus infections averted. Most studies used mathematical modeling and projected OPC outcomes using the experience of a single facility in Vancouver, BC.
conclusionsOPCs were found to be cost-saving or to have favorable cost-effectiveness or cost-benefit ratios across all studies. Future studies should incorporate the experience of OPCs established in various settings and use a greater diversity of modeling designs.
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Registered trials
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