Evidence map›Paper›PMID 38401451›Full record

ArticleComputers in biology and medicine2024

Directed Graph Mapping exceeds Phase Mapping for the detection of simulated 2D meandering rotors in fibrotic tissue with added noise.

Sebastiaan Lootens, Iris Janssens, Robin Van Den Abeele, Eike M Wülfers, Arthur Santos Bezerra, Bjorn Verstraeten, Sander Hendrickx, Arstanbek Okenov, Timur Nezlobinsky, Alexander V Panfilov and 1 more

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Role of interatrial connection ablation in re-entry dynamics: an in silico evaluation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sebastiaan LootensDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium. Electronic address: sebastiaan.lootens@ugent.be.
Iris JanssensDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Robin Van Den AbeeleDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Eike M WülfersDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Arthur Santos BezerraDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Bjorn VerstraetenDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Sander HendrickxDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Arstanbek OkenovDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Timur NezlobinskyDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.
Alexander V PanfilovDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium; World-Class Research Center "Digital Biodesign and personalised healthcare", Sechenov University, Moscow 119991, Russia; Laboratory of Computational Biology and Medicine, Ural Federal University, Ekaterinburg 620002, Russia.
Nele VandersickelDepartment of Physics and Astronomy, Ghent University, Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrhythmias such as atrial fibrillation (AF) are recognised to be associated with re-entry or rotors. A rotor is a wave of excitation in the cardiac tissue that wraps around its refractory tail, causing faster-than-normal periodic excitation. The detection of rotor centres is of crucial importance in guiding ablation strategies for the treatment of arrhythmia. The most popular technique for detecting rotor centres is Phase Mapping (PM), which detects phase singularities derived from the phase of a signal. This method has been proven to be prone to errors, especially in regimes of fibrotic tissue and temporal noise. Recently, a novel technique called Directed Graph Mapping (DGM) was developed to detect rotational activity such as rotors by creating a network of excitation. This research aims to compare the performance of advanced PM techniques versus DGM for the detection of rotors using 64 simulated 2D meandering rotors in the presence of various levels of fibrotic tissue and temporal noise. Four strategies were employed to compare the performances of PM and DGM. These included a visual analysis, a comparison of F

Indexed as

Atrial FibrillationCatheter AblationFibrosisHeartHumansTime FactorsDirected Graph MappingFibrosisMeanderingNoisePerformance comparisonPhase MappingSimulated rotors

Identifiers

PMID38401451
PMCPMC10966475

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.