Evidence map›Paper›PMID 38401050›Full record

ArticleJournal of medicinal chemistry2024

Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver(I) Compounds Bearing Phosphane Coligands.

Ricardo G Teixeira, Alessia Stefanelli, Adhan Pilon, Rebecca Warmers, Xavier Fontrodona, Isabel Romero, Paulo J Costa, Maria J Villa de Brito, Xenia Hudec, Christine Pirker and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Paraptosis-A Distinct Pathway to Cell Death.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 5 countries.

Ricardo G TeixeiraCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa 1749-016, Portugal.
Alessia StefanelliCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.
Adhan PilonCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa 1749-016, Portugal.
Rebecca WarmersCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.
Xavier FontrodonaDepartament de Química and Serveis Tècnics de Recerca, Universitat de Girona, Campus de Montilivi, Girona 17071, Spain.
Isabel RomeroDepartament de Química and Serveis Tècnics de Recerca, Universitat de Girona, Campus de Montilivi, Girona 17071, Spain.ORCID 0000-0003-4805-8394
Paulo J CostaBioISI - Instituto de Biosistemas e Ciências Integrativas, Faculdade de Ciências, Universidade de Lisboa, Lisboa 1749-016, Portugal.ORCID 0000-0002-0492-6666
Maria J Villa de BritoCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa 1749-016, Portugal.
Xenia HudecCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.
Christine PirkerCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.
Sebastian TürckInstitute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstr. 55, Braunschweig 38106, Germany.
Alexandra M M AntunesCentro de Química Estrutural (CQE), Institute of Molecular Sciences, Departamento de Engenharia Química, Instituto Superior Técnico (IST), Universidade de Lisboa, Av Rovisco Pais 1, Lisboa 1049-001, Portugal.ORCID 0000-0003-1827-7369
Christian R KowolInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringerstrasse 42, Vienna 1090, Austria.ORCID 0000-0002-8311-1632
Ingo OttInstitute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstr. 55, Braunschweig 38106, Germany.ORCID 0000-0002-8087-4618
Anamaria BrozovicDivision of Molecular Biology, Ruđer Bošković Institute, Bijenička cesta 54,Zagreb 10000, Croatia.
Andy SombkeCenter for Anatomy and Cell Biology, Cell and Developmental Biology, Medical University of Vienna, Schwarzspanierstraße 17, Vienna 1090, Austria.
Margret EckhardCenter for Anatomy and Cell Biology, Cell and Developmental Biology, Medical University of Vienna, Schwarzspanierstraße 17, Vienna 1090, Austria.
Ana Isabel TomazCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa 1749-016, Portugal.
Petra HeffeterCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Vienna 1090, Austria.
Andreia ValenteCentro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa 1749-016, Portugal.ORCID 0000-0002-3370-208X
University of Lisbon · PTComprehensive Cancer Center Vienna · ATMedical University of Vienna · ATTechnische Universität Braunschweig · DEUniversitat de Girona · ESRuđer Bošković Institute · HRUniversity of Vienna · AT

Funding

INSTRUMENTAL ANALYSISZ01CT000014 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI WEISS, GEORGE H · 1985 to 2008
$408k
Austrian Science Fund FWF DOC 59Intramural NIH HHS Z01 CT000014
6 · The paper itself

Abstract

In this work, we investigated the anticancer activity of several novel silver(I) 2,2'-bipyridine complexes containing either triphenylphosphane (PPh

Indexed as

2,2'-DipyridylAntineoplastic AgentsPhosphinesSilverApoptosisCell DeathCell Line, TumorCoordination ComplexesCrystallography, X-RayDrug Resistance, NeoplasmDrug Screening Assays, AntitumorHumansLigandsStructure-Activity Relationship2,2'-DipyridylAntineoplastic AgentsCoordination ComplexesLigandsphosphinePhosphinesSilver

Identifiers

PMID38401050
PMCPMC11056982
OpenAlexW4392130745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.