Evidence map›Paper›PMID 38400991›Full record

ArticleJournal of ultrasound2024

An unusual case of metastatic melanoma in subcutaneous tissue presenting as a solitary cystic mass with fluid levels.

Catherine Cubitt, Sisith Ariyaratne, Sumathi Vaiyapuri, Vineet Kurisunkal, Rajesh Botchu

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of ultrasound, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Catherine CubittCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Sisith AriyaratneDepartment of Musculoskeletal Radiology, The Royal Orthopaedic Hospital, Birmingham, UK. sisithariyaratne@gmail.com.ORCID http://orcid.org/0000-0002-7377-028X
Sumathi VaiyapuriDepartment of Pathology, University Hospitals Birmingham, Birmingham, UK.
Vineet KurisunkalDepartment of Orthopaedic Oncology, The Royal Orthopaedic Hospital, Birmingham, UK.
Rajesh BotchuDepartment of Musculoskeletal Radiology, The Royal Orthopaedic Hospital, Birmingham, UK.
Royal Orthopaedic Hospital · GBNIHR Surgical Reconstruction and Microbiology Research Centre · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant melanoma is a common and often aggressive neoplasm of the skin arising from melanocytes. Metastatic melanoma is known for its diverse clinical manifestations, and can present with atypical features prior to diagnosis of the primary lesion, which can pose a diagnostic challenge. We report a rare case of metastatic melanoma in a 67 year-old male who presented with a painless, enlarging mass in the right axilla over a 4 week period. Ultrasound and magnetic resonance imaging (MRI) scans revealed a well-defined solitary, cystic appearing lesion in the right axilla with a distinct fluid-fluid level. An ultrasound guided biopsy of the lesion diagnosed a metastatic melanoma. While haemorrhagic distant metastases are a well-recognised complication of malignant melanoma, particularly in the brain and lung, soft tissue metastases presenting with fluid-fluid levels is not well described in the literature. The case highlights the importance of considering the differential of melanoma metastasis when encountered with such a lesion and importance of ultrasound guided biopsy for histopathological confirmation, as the imaging features can mimic that of a haemorrhagic soft tissue sarcoma, the management of which differs substantially from that of melanoma.

Indexed as

Magnetic Resonance ImagingMelanomaSkin NeoplasmsSubcutaneous TissueAgedAxillaCystsDiagnosis, DifferentialHumansImage-Guided BiopsyMaleSoft Tissue NeoplasmsUltrasonographyFluid levelMagnetic resonance imagingMelanoma metastasisSoft tissue massUltrasound

Identifiers

PMID38400991
PMCPMC11496403
OpenAlexW4392131837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.