Evidence map›Paper›PMID 38400990›Full record

ArticleCell biochemistry and biophysics2024

Changes of LncRNAs during the Process of Antioxidants Antagonize Cadmium-Induced Oxidative Damage in Islet β Cells.

Rongxian Li, Jiao Dai, Zuoshun He, Shiyan Gu

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rongxian Li *Institute of Preventive Medicine, School of Public Health, Dali University, Dali, Yunnan, China.ORCID http://orcid.org/0009-0004-3094-2397
Jiao Dai *Qujing Medical College, Qujing, Yunnan, China.ORCID http://orcid.org/0000-0002-7006-2261
Zuoshun HeInstitute of Preventive Medicine, School of Public Health, Dali University, Dali, Yunnan, China. hzs338@163.com.ORCID http://orcid.org/0000-0003-3796-7779
Shiyan GuInstitute of Preventive Medicine, School of Public Health, Dali University, Dali, Yunnan, China. ygsy727@163.com.ORCID http://orcid.org/0000-0003-4278-2509
Dali University · CNQujing Normal University · CN

Funding

The Joint Special Fund for Basic Research in Chinese Medicine, Yunnan Provincial Science and Technology Department NO.202101AZ070001-085
6 · The paper itself

Abstract

Long non-coding RNAs (LncRNAs) play important regulatory roles in oxidative damage. Resveratrol, curcumin, and cyanidin are phytogenic antioxidants widely existing in nature and they have been proved to antagonize certain heavy metal-induced oxidative damage in cells. However, can they antagonize oxidative damage induced by cadmium in islet β cells? Are their mechanisms of antagonizing oxidative damage related to LncRNAs? In this study, we first detected the cell viability of each group by CCK8 assay. Next, reactive oxygen species (ROS) were detected by the fluorescent probe. The contents of malondialdehyde (MDA) and the activities of superoxide dismutase (SOD) were detected according to the instructions of corresponding kits. At last, the levels of LncRNAs were detected by fluorescence quantitative real-time polymerase chain reaction (qPCR). The results showed that resveratrol, curcumin and cyanidin were able to reverse the reduction of cell viability induced by cadmium (CdSO

Indexed as

AnthocyaninsAntioxidantsCadmiumCell SurvivalCurcuminInsulin-Secreting CellsMalondialdehydeOxidative StressReactive Oxygen SpeciesResveratrolRNA, Long NoncodingSuperoxide DismutaseAnimalsCell LineAnthocyaninsAntioxidantsCadmiumCurcumincyanidinMalondialdehydeReactive Oxygen SpeciesResveratrolRNA, Long NoncodingSuperoxide DismutaseAntioxidantsCadmiumIslet β cellsLong non-coding RNAsOxidative damage

Identifiers

PMID38400990
OpenAlexW4392128944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.