Evidence map›Paper›PMID 38400892›Full record

ArticleMedical oncology (Northwood, London, England)2024

Exploring the Potential of Essential Oil from Plectranthus amboinicus Leaves against Breast Cancer: In vitro and In silico Analysis.

Khushi Gupta, Pranay Gautre, Avadh Biharee, Yogesh Singh, Umesh Kumar Patil, Shashank Kumar, Suresh Thareja

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Khushi Gupta *Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India.ORCID http://orcid.org/0009-0005-1486-1201
Pranay Gautre *Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India.ORCID http://orcid.org/0009-0008-6363-6432
Avadh BihareeDepartment of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India.ORCID http://orcid.org/0000-0003-0153-2941
Yogesh SinghDepartment of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India.ORCID http://orcid.org/0000-0001-5626-1486
Umesh Kumar PatilDepartment of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, 470003, M.P, India.ORCID http://orcid.org/0000-0002-2096-9922
Shashank KumarMolecular Signaling & Drug Discovery Laboratory, Department of Biochemistry, Central University of Punjab, Bathinda, 151 401, Punjab, India. shashankbiochemau@gmail.com.ORCID http://orcid.org/0000-0002-9622-0512
Suresh TharejaDepartment of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, 151401, Punjab, India. sureshthareja@gmail.com.ORCID http://orcid.org/0000-0001-7668-462X
Central University of Punjab · INDr. Hari Singh Gour University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plectranthus amboinicus leaves were subjected to hydrodistillation to obtain essential oil (EO). Phytochemical analysis using gas chromatography-mass spectrometry revealed a diverse range of compounds in the EO, with p-cymen-4-ol (18.57%) emerging as the most predominant, followed by isocaryophyllene (12.18%). The in vitro antiproliferative activity of EO against breast cancer was assessed in MCF-7 and MDA-MB-231 cell lines. The MTT assay results revealed that EO showed IC

Indexed as

Breast NeoplasmsOils, VolatilePlectranthusAnastrozoleAromataseFemaleHumansLetrozoleMolecular Docking SimulationAnastrozoleAromataseLetrozoleOils, VolatileBreast cancerEssential oilMolecular dockingMolecular dynamics simulationPlectranthus amboinicus

Identifiers

PMID38400892
OpenAlexW4392132052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.