ReviewAdvanced healthcare materials2024
Hierarchical Design of Tissue-Mimetic Fibrillar Hydrogel Scaffolds.
Review in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Hydrogel nanofiber-based 3D cell cultures and organoids.Chemical science · 2026Review
- Elastic scaffolds reinforced stem cell-laden collagen-derived hybrid hydrogels to engineer 3D anisotropic cellular microenvironment.Materials today. Bio · 2026Article
- Linker Molar Mass-Driven Control over Supramolecular Network Relaxation and Architecture in BTA Hydrogels.Macromolecules · 2026Article
- Mechanisms of Impaired Skeletal Muscle Regeneration and Therapeutic Approaches in Aging and Chronic Disease.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Lipoengineering of Biomolecular Condensates Controls Material Properties and Multiphase Hierarchy to Guide Organoid Morphogenesis.bioRxiv : the preprint server for biology · 2026Article
- Quantitative Assessment of Hydrogel Printability in Extrusion Bioprinting.Gels (Basel, Switzerland) · 2026Review
- Omnidirectional 3D Printing of Anisotropic Nanofibrous Peptide Hydrogels.bioRxiv : the preprint server for biology · 2025Article
- Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts.Advanced healthcare materials · 2025Article
- Hydrogel Network Architecture Design Space: Impact on Mechanical and Viscoelastic Properties.Gels (Basel, Switzerland) · 2025Review
- Filamented Light (FLight) Biofabrication of Aligned Fibrillar Structures to Direct 3D Cell Organization Within Microgels.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Stimulus-responsive cellulose hydrogels in biomedical applications and challenges.Materials today. Bio · 2025Review
- Recent Development of Fibrous Hydrogels: Properties, Applications and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Omnidirectional anisotropic embedded 3D bioprinting.Materials today. Bio · 2024Article
- Hierarchical Design of Tissue-Mimetic Fibrillar Hydrogel Scaffolds.Advanced healthcare materials · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Most tissues of the human body present hierarchical fibrillar extracellular matrices (ECMs) that have a strong influence over their physicochemical properties and biological behavior. Of great interest is the introduction of this fibrillar structure to hydrogels, particularly due to the water-rich composition, cytocompatibility, and tunable properties of this class of biomaterials. Here, the main bottom-up fabrication strategies for the design and production of hierarchical biomimetic fibrillar hydrogels and their most representative applications in the fields of tissue engineering and regenerative medicine are reviewed. For example, the controlled assembly/arrangement of peptides, polymeric micelles, cellulose nanoparticles (NPs), and magnetically responsive nanostructures, among others, into fibrillar hydrogels is discussed, as well as their potential use as fibrillar-like hydrogels (e.g., those from cellulose NPs) with key biofunctionalities such as electrical conductivity or remote stimulation. Finally, the major remaining barriers to the clinical translation of fibrillar hydrogels and potential future directions of research in this field are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.