Evidence map›Paper›PMID 38400634›Full record

ArticleAge and ageing2024

Adherence to the Atrial fibrillation Better Care pathway and the risk of adverse health outcomes in older care home residents with atrial fibrillation: a retrospective data linkage study 2003-18.

Leona A Ritchie, Stephanie L Harrison, Peter E Penson, Ashley Akbari, Fatemeh Torabi, Joe Hollinghurst, Daniel Harris, Oluwakayode B Oke, Asangaedem Akpan, Julian P Halcox and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Age and ageing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Leona A RitchieLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.ORCID 0000-0002-0392-1767
Stephanie L HarrisonLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.ORCID 0000-0002-8846-0946
Peter E PensonLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.ORCID 0000-0001-6763-1489
Ashley AkbariPopulation Data Science, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Fatemeh TorabiPopulation Data Science, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Joe HollinghurstPopulation Data Science, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Daniel HarrisPopulation Data Science, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Oluwakayode B OkeDepartment of Renal Medicine, East Kent Hospital NHS Foundation Trust, Ashford TN24 0LZ, UK.
Asangaedem AkpanDepartment of Geriatric Medicine, Bunbury Regional Hospital, WA Country Health Service - South West, Bunbury 6230, Australia.
Julian P HalcoxPopulation Data Science, Swansea University Medical School, Swansea University, Swansea, Wales SA2 8PP, UK.
Sarah E RodgersDepartment of Public Health, Policy and Systems, Institute of Population Health, University of Liverpool, Liverpool L69 3GF, UK.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
Deirdre A LaneLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
University of Liverpool · GBSwansea University · GBEast Kent Hospitals University NHS Foundation Trust · GBThe University of Western Australia · AU

Funding

British Heart FoundationWellcome Trust
6 · The paper itself

Abstract

backgroundThe Atrial fibrillation Better Care (ABC) pathway is the gold-standard approach to atrial fibrillation (AF) management, but the effect of implementation on health outcomes in care home residents is unknown.

objectiveTo examine associations between ABC pathway adherence and stroke, transient ischaemic attack, cardiovascular hospitalisation, major bleeding, mortality and a composite of all these outcomes in care home residents.

methodsA retrospective cohort study of older care home residents (≥65 years) in Wales with AF was conducted between 1 January 2003 and 31 December 2018 using the Secure Anonymised Information Linkage Databank. Adherence to the ABC pathway was assessed at care home entry using pre-specified definitions. Cox proportional hazard and competing risk models were used to estimate the risk of health outcomes according to ABC adherence.

resultsFrom 14,493 residents (median [interquartile range] age 87.0 [82.6-91.2] years, 35.2% male) with AF, 5,531 (38.2%) were ABC pathway adherent. Pathway adherence was not significantly associated with risk of the composite outcome (adjusted hazard ratio, 95% confidence interval [CI]: 1.01 [0.97-1.05]). There was a significant independent association observed between ABC pathway adherence and a reduced risk of myocardial infarction (0.70 [0.50-0.98]), but a higher risk of haemorrhagic stroke (1.59 [1.06-2.39]). ABC pathway adherence was not significantly associated with any other individual health outcomes examined.

conclusionAn ABC adherent approach in care home residents was not consistently associated with improved health outcomes. Findings should be interpreted with caution owing to difficulties in defining pathway adherence using routinely collected data and an individualised approach is recommended.

Indexed as

Atrial FibrillationAgedAged, 80 and overAnticoagulantsCritical PathwaysFemaleHumansInformation Storage and RetrievalMaleOutcome Assessment, Health CareRetrospective StudiesAnticoagulantsatrial fibrillationcare homeshealth outcomesintegrated careolder people

Identifiers

PMID38400634
PMCPMC10891424
OpenAlexW4392149076

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.