Evidence map›Paper›PMID 38400188›Full record

ArticleVaccines2024

Genital and Oral HPV Geno-Prevalence Measured through Urine and Saliva Samples in Young Adults in Italy.

Francesco Napolitano, Silvia Angelillo, Aida Bianco, Gabriella Di Giuseppe, Valeria Di Onofrio, Francesca Licata, Giorgio Liguori, Carmelo Giuseppe Angelo Nobile, Maria Pavia, Concetta Paola Pelullo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Francesco NapolitanoDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4694-2418
Silvia AngelilloDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-8103-5368
Aida BiancoDepartment of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-4674-0306
Gabriella Di GiuseppeDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-4466-6683
Valeria Di OnofrioDepartment of Sciences and Technologies, University of Naples "Parthenope", 80143 Naples, Italy.ORCID 0000-0001-9398-3496
Francesca LicataDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-3704-6822
Giorgio LiguoriDepartment of Medical, Movement and Wellbeing Sciences, University of Naples "Parthenope", 80133 Naples, Italy.
Carmelo Giuseppe Angelo NobileDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.ORCID 0000-0002-0762-513X
Maria PaviaDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-3879-1322
Concetta Paola PelulloDepartment of Medical, Movement and Wellbeing Sciences, University of Naples "Parthenope", 80133 Naples, Italy.ORCID 0000-0003-4228-8703
Federica Zito MarinoDepartment of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Italo Francesco AngelilloDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-1213-6602
University of Campania "Luigi Vanvitelli" · ITMagna Graecia University · ITParthenope University of Naples · ITUniversity of Calabria · IT

Funding

Italian Ministry of University and Research (MUR) PRIN 2017: 20177MKB4H.
6 · The paper itself

Abstract

backgroundThe aims of the study were to determine, in the urine and oral samples of young adults, the genotype-specific prevalence of Human Papilloma Virus (HPV) infection, the HPV DNA type-specific prevalence in unvaccinated and vaccinated individuals, and the determinants of HPV infection.

methodsSelected participants were asked to fill in a self-administered questionnaire and to self-collect urine and saliva samples.

resultsAmong the 1002 participants, 81 (8.1%) resulted positive for HPV DNA. The most common low-risk genotype was HPV 42 (2.2%), followed by HPV 43 (0.8%), and 40 (0.5%). The HPV 51 was the most common high-risk genotype (1.5%) followed by HPV 66 (1%) and HPV 68 (1%), and no participants were infected with HPV genotypes 18, 33, 45. Females, those who have had one or more occasional sexual partner, those who never/rarely/sometimes used condoms during their sexual activity, those with a previous diagnosis of sexually transmitted infection, and those who were not vaccinated were more likely to be tested positive for HPV infection.

conclusionsThe low prevalence of genital HPV infections has provided evidence of the effectiveness of HPV vaccination both in vaccinated and not yet vaccinated subjects through herd immunity and indicated its decisive role in the changing epidemiology of circulating HPV genotypes in the population.

Indexed as

geno-prevalenceHPV vaccinationsalivaurineyoung adults

Identifiers

PMID38400188
PMCPMC10892725
OpenAlexW4391948776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.