Evidence map›Paper›PMID 38400184›Full record

ArticleVaccines2024

A Practical Guide to Full Value of Vaccine Assessments.

Caroline Trotter, Birgitte Giersing, Ann Lindstrand, Naor Bar-Zeev, Tania Cernuschi, Lauren Franzel-Sassanpour, Martin Friede, Joachim Hombach, Maarten Jansen, Mateusz Hasso-Agopsowicz and 5 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Caroline TrotterDisease Dynamics Unit, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.ORCID 0000-0003-4000-2708
Birgitte GiersingImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Ann LindstrandImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0002-8271-9486
Naor Bar-ZeevImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Tania CernuschiImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Lauren Franzel-SassanpourImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Martin FriedeImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Joachim HombachImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0002-3271-6033
Maarten JansenImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Mateusz Hasso-AgopsowiczImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
Mitsuki KohImmunization Department, World Health Organization, 1202 Geneva, Switzerland.
So Yoon SimImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0002-3267-1867
Dijana SpasenoskaImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0003-3640-4405
Karene Hoi Ting YeungImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0001-9225-7935
Philipp LambachImmunization Department, World Health Organization, 1202 Geneva, Switzerland.ORCID 0000-0003-0105-8899
World Health Organization · CHUniversity of Cambridge · GB

Funding

World Health Organization 001
6 · The paper itself

Abstract

Articulating the wide range of health, social and economic benefits that vaccines offer may help to overcome obstacles in the vaccine development pipeline. A framework to guide the assessment and communication of the value of a vaccine-the Full Value of Vaccine Assessment (FVVA)-has been developed by the WHO. The FVVA framework offers a holistic assessment of the value of vaccines, providing a synthesis of evidence to inform the public health need of a vaccine, describing the supply and demand aspects, its market and its impact from a health, financial and economic perspective. This paper provides a practical guide to how FVVAs are developed and used to support investment in vaccines, ultimately leading to sustained implementation in countries. The FVVA includes a range of elements that can be broadly categorised as synthesis, vaccine development narrative and defining vaccine impact and value. Depending on the features of the disease/vaccine in question, different elements may be emphasised; however, a standardised set of elements is recommended for each FVVA. The FVVA should be developed by an expert group who represent a range of stakeholders, perspectives and geographies and ensure a fair, coherent and evidence-based assessment of vaccine value.

Indexed as

full value of vaccine assessmentvaccine developmentvaccine pipelinevaccine value

Identifiers

PMID38400184
PMCPMC10892982
OpenAlexW4391882514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.