ReviewVaccines2024
Human Tick-Borne Diseases and Advances in Anti-Tick Vaccine Approaches: A Comprehensive Review.
Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- African tick-borne viruses: A systematic review of diversity, epidemiology, clinical impact, and one health strategies.Veterinary research communications · 2026Pooled it
- Global trends in tick research: a comprehensive visualization and bibliometric study (2015-2024).Frontiers in cellular and infection microbiology · 2025Pooled it
- Tick Microbiome and Its Role in Emerging Zoonotic Diseases and Transmissibility.Microorganisms · 2026Review
- Environmental degradation as a recipe for emerging viral diseases: implications for global health.One health outlook · 2026Review
- Tick-Borne Co-Infection in Lyme Disease: Clinical Impact, Diagnostic Challenges, and Therapeutic Perspectives.Microorganisms · 2026Review
- Tick-associated microorganisms (Current research in parasitology & vector-borne diseases · 2026Article
- Pooled prevalence, species diversity, and risk factors of ixodid ticks in Ethiopian domestic animals: A systematic review and meta-analysis.Current research in parasitology & vector-borne diseases · 2026Review
- Tick threats in the context of climate change: One Health response strategies in the Middle East and North Africa region.Science in One Health · 2026Review
- Knowledge, attitudes, and practices of cattle farmers regarding ticks, tick-borne diseases, and zoonotic risks in Borno State, Nigeria: A cross-sectional survey.Veterinary world · 2025Article
- First report of VGSC mutations for resistance to synthetic pyrethroids in brown dog ticks (Rhipicephalus sanguineus sensu stricto) from Brazil.Parasites & vectors · 2025Article
- Review
- Human babesiosis: The past, present and future.Expert reviews in molecular medicine · 2025Review
- Meeting Report on an Integrated Research Agenda for Mosquito-Borne Arboviruses.Open forum infectious diseases · 2025Article
- Fourteen anti-tick vaccine targets are variably conserved in cattle fever ticks.Parasites & vectors · 2025Article
- Tick feeding or vaccination with tick antigens elicits immunity to theScience translational medicine · 2025Article
- Ticks (Acari: Ixodidae) and tick-borne diseases affecting communal cattle and the control methods practiced by farmers in the Eastern Cape Province of South Africa.Veterinary world · 2025Article
- Current Tick Control Strategies and Prospects for Using Nanotechnology as an Efficient Alternative-A Review.Veterinary sciences · 2025Review
- Tick Control Strategies: Critical Insights into Chemical, Biological, Physical, and Integrated Approaches for Effective Hard Tick Management.Veterinary sciences · 2025Review
- Ticks and tick-borne diseases in the northern hemisphere affecting humans.Frontiers in microbiology · 2025Review
- A review of acaricides and their resistance mechanisms in hard ticks and control alternatives with synergistic agents.Acta tropica · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This comprehensive review explores the field of anti-tick vaccines, addressing their significance in combating tick-borne diseases of public health concern. The main objectives are to provide a brief epidemiology of diseases affecting humans and a thorough understanding of tick biology, traditional tick control methods, the development and mechanisms of anti-tick vaccines, their efficacy in field applications, associated challenges, and future prospects. Tick-borne diseases (TBDs) pose a significant and escalating threat to global health and the livestock industries due to the widespread distribution of ticks and the multitude of pathogens they transmit. Traditional tick control methods, such as acaricides and repellents, have limitations, including environmental concerns and the emergence of tick resistance. Anti-tick vaccines offer a promising alternative by targeting specific tick proteins crucial for feeding and pathogen transmission. Developing vaccines with antigens based on these essential proteins is likely to disrupt these processes. Indeed, anti-tick vaccines have shown efficacy in laboratory and field trials successfully implemented in livestock, reducing the prevalence of TBDs. However, some challenges still remain, including vaccine efficacy on different hosts, polymorphisms in ticks of the same species, and the economic considerations of adopting large-scale vaccine strategies. Emerging technologies and approaches hold promise for improving anti-tick vaccine development and expanding their impact on public health and agriculture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.