Evidence map›Paper›PMID 38400124›Full record

ArticleVaccines2024

Long-Term Immunogenicity and Safety of a Homologous Third Dose Booster Vaccination with TURKOVAC: Phase 2 Clinical Study Findings with 32-Week Post-Booster Follow-Up.

Zafer Sezer, Shaikh Terkis Islam Pavel, Ahmet Inal, Hazel Yetiskin, Busra Kaplan, Muhammet Ali Uygut, Ahmet Furkan Aslan, Adnan Bayram, Mumtaz Mazicioglu, Gamze Kalin Unuvar and 6 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zafer SezerDepartment of Medical Pharmacology, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.
Shaikh Terkis Islam PavelVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.ORCID 0000-0002-7178-0943
Ahmet InalDepartment of Medical Pharmacology, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.
Hazel YetiskinVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.
Busra KaplanVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.ORCID 0000-0002-2029-6270
Muhammet Ali UygutVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.
Ahmet Furkan AslanVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.
Adnan BayramDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.ORCID 0000-0002-6700-8301
Mumtaz MaziciogluDepartment of Family Medicine, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.ORCID 0000-0002-6458-2906
Gamze Kalin UnuvarDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.
Zeynep Ture YuceDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Kayseri 38280, Türkiye.
Gunsu AydinVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.
Refika Kamuran KayaHealth Institutes of Türkiye (TUSEB), Istanbul 34718, Türkiye.
Ihsan AtesDepartment of Internal Medicine, University of Health Sciences Ankara City Hospital, Ankara 06530, Türkiye.
Ates KaraHealth Institutes of Türkiye (TUSEB), Istanbul 34718, Türkiye.ORCID 0000-0002-1654-3232
Aykut OzdarendeliVaccine Research, Development and Application Centre (ERAGEM), Erciyes University, Kayseri 38280, Türkiye.

Funding

Health Institutes of Turkiye (TUSEB), Erciyes University Health Institutes of Turkiye (TUSEB) (with grant ID:11484) and Erciyes University (with grant ID:9644 and with grant ID:11418).
6 · The paper itself

Abstract

Vaccine-induced immunity wanes over time and warrants booster doses. We investigated the long-term (32 weeks) immunogenicity and safety of a third, homologous, open-label booster dose of TURKOVAC, administered 12 weeks after completion of the primary series in a randomized, controlled, double-blind, phase 2 study. Forty-two participants included in the analysis were evaluated for neutralizing antibodies (NAbs) (with microneutralization (MNT

Indexed as

boosterCOVID-19immunogenicityinactivated vaccineneutralizing antibodyS1 RBDsafetySARS-CoV-2seroconversionTURKOVAC

Identifiers

PMID38400124
PMCPMC10893411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.