Evidence map›Paper›PMID 38400046›Full record

ArticleViruses2024

COVID-19 Outcomes and Vaccinations in Swedish Solid Organ Transplant Recipients 2020-2021: A Nationwide Multi-Register Comparative Cohort Study.

John Mackay Søfteland, Huiqi Li, Jesper M Magnusson, Susannah Leach, Vanda Friman, Magnus Gisslén, Marie Felldin, Andreas Schult, Kristjan Karason, Seema Baid-Agrawal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

John Mackay SøftelandThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0000-0001-7993-5906
Huiqi LiSchool of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0002-1127-0829
Jesper M MagnussonThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0000-0002-5630-0155
Susannah LeachDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0002-9614-2753
Vanda FrimanDepartment of Infectious Diseases, Sahlgrenska University Hospital, 41685 Gothenburg, Sweden.ORCID 0000-0002-0361-4222
Magnus GisslénDepartment of Infectious Diseases, Sahlgrenska University Hospital, 41685 Gothenburg, Sweden.ORCID 0000-0002-2357-1020
Marie FelldinThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Andreas SchultThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Kristjan KarasonThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0000-0002-2802-1191
Seema Baid-AgrawalThe Transplant Institute, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.ORCID 0000-0001-8192-1079
Carin WallquistDepartment of Nephrology, Skåne University Hospital, 21428 Malmö, Sweden.ORCID 0000-0001-7063-2925
Fredrik NybergSchool of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0003-0892-5668
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased COVID-19-related morbidity and mortality have been reported in solid organ transplant recipients (SOTRs). Most studies are underpowered for rigorous matching. We report infections, hospitalization, ICU care, mortality from COVID-19, and pertinent vaccination data in Swedish SOTRs 2020-2021. We conducted a nationwide cohort study, encompassing all Swedish residents. SOTRs were identified with ICD-10 codes and immunosuppressant prescriptions. Comparison cohorts were weighted based on a propensity score built from potential confounders (age, sex, comorbidities, socioeconomic factors, and geography), which achieved a good balance between SOTRs and non-SOTR groups. We included 10,372,033 individuals, including 9073 SOTRs. Of the SARS-CoV-2 infected, 47.3% of SOTRs and 19% of weighted comparator individuals were hospitalized. ICU care was given to 8% of infected SOTRs and 2% of weighted comparators. The case fatality rate was 7.7% in SOTRs, 6.2% in the weighted comparison cohort, and 1.3% in the unweighted comparison cohort. SOTRs had an increased risk of contracting COVID-19 (HR = 1.15

Indexed as

COVID-19Organ TransplantationCohort StudiesHumansSARS-CoV-2SwedenTransplant RecipientsVaccinationCOVID-19immunosuppressionsolid organ transplant recipientstransplantationvaccines

Identifiers

PMID38400046
PMCPMC10893154
OpenAlexW4391691421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.