Evidence map›Paper›PMID 38399970›Full record

ArticleViruses2024

Simplified Criteria to Assess Long-Term Antiviral Treatment Indication in Chronic HBV-Infected Pregnant Women in Cambodia.

Jee-Seon Yang, Saren Sovann, Yusuke Shimakawa, Sovann Nhoueng, Bunnet Dim, Chanlina Vong, Channa Sann, Julia Guillebaud, Darapolin Vann, Bunrith Touch and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 4 countries.

Jee-Seon YangInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.ORCID 0000-0002-4209-280X
Saren SovannInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Yusuke ShimakawaInstitut Pasteur, Unité d'Épidémiologie des Maladies Émergentes, Université Paris Cité, 75015 Paris, France.ORCID 0000-0002-4198-4785
Sovann NhouengInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Bunnet DimInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Chanlina VongCalmette Hospital, Phnom Penh 12201, Cambodia.
Channa SannCalmette Hospital, Phnom Penh 12201, Cambodia.
Julia GuillebaudInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Darapolin VannJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Bunrith TouchJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Hyna CheaJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Wathanak Pisey Choupoan PhirumJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Eric RosenthalANRS|Maladies Infectieuses Emergentes, 75000 Paris, France.
Christelle PaulANRS|Maladies Infectieuses Emergentes, 75000 Paris, France.
Leangchhun KhunJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Chantana YayJayavarman VII Hospital, Siem Reap 17259, Cambodia.
Denis LaurentDirection Department, Foundation Children's Hospital Kantha Bopha, Phnom Penh 12000, Cambodia.
Samsorphea ChhunCalmette Hospital, Phnom Penh 12201, Cambodia.
Laurence BorandInstitut Pasteur du Cambodge, Phnom Penh 12201, Cambodia.
Olivier SegeralANRS|Maladies Infectieuses Emergentes, 75000 Paris, France.
Institut Pasteur du Cambodge · KHCalmette Hospital · KHInstitut Pasteur · FRJohns Hopkins University · USSorbonne Université · FRUniversité Côte d'Azur · FRUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnant women identified to carry hepatitis B surface antigen (HBsAg) should be linked to care for the determination of the need for long-term antiviral therapy (LTT). We assessed the performance of simplified criteria, free from HBV DNA quantification, to select women eligible for LTT using different international guidelines as a reference. A retrospective analysis of HBV-infected pregnant women enrolled in the phase 4 ANRS TA-PROHM study was conducted in Cambodia. Sensitivity, specificity, and AUROC were computed to compare three simplified criteria (TREAT-B, HBcrAg/ALT, and TA-PROHM) with the American (AASLD) and European (EASL) guidelines as a reference. An additional assessment was performed at 6 months postpartum. Of 651 HBsAg-positive women, 209 (32%) received peripartum antiviral prophylaxis using tenofovir disoproxil fumarate (TDF). During pregnancy, 9% and 12% of women were eligible for LTT according to AASLD and EASL guidelines, respectively; 21% and 24% of women were eligible for prophylactic TDF and 2% and 5% in those ineligible (

Indexed as

Hepatitis B, ChronicPregnancy Complications, InfectiousAntiviral AgentsCambodiaDNA, ViralFemaleHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansInfectious Disease Transmission, VerticalPregnancyPregnant PeopleRetrospective StudiesTenofovirAntiviral AgentsDNA, ViralHepatitis B e AntigensHepatitis B Surface AntigensTenofovirhepatitis Binternational guidelineslong-term treatmentpostpartumpregnancypublic health

Identifiers

PMID38399970
PMCPMC10891875
OpenAlexW4391315426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.