Evidence map›Paper›PMID 38399962›Full record

ArticleViruses2024

Factors Associated with SARS-CoV-2 Infection in Fully Vaccinated Nursing Home Residents and Workers.

Jesús Mateos-Nozal, Mario Rodríguez-Domínguez, Jesús San Román, Francisco Javier Candel, Noelia Villarrubia, Nuria Pérez-Panizo, Esther Segura, Juan Manuel Cuñarro, Manuel V Mejía Ramírez-Arellano, Rafael Rodríguez-Ramos and 6 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Jesús Mateos-NozalServicio de Geriatría, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-5833-4407
Mario Rodríguez-DomínguezServicio de Microbiología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-1783-9318
Jesús San RománLaboratorio Regional de Salud Pública, 28053 Madrid, Spain.ORCID 0000-0003-4242-0436
Francisco Javier CandelServicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital Clínico San Carlos, 28040 Madrid, Spain.ORCID 0000-0002-9840-6556
Noelia VillarrubiaServicio de Inmunología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-2114-8632
Nuria Pérez-PanizoServicio de Geriatría, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-3223-0834
Esther SeguraResidencia de Mayores Manoteras, 28050 Madrid, Spain.
Juan Manuel CuñarroResidencia de Mayores Adolfo Suárez, 28032 Madrid, Spain.ORCID 0009-0001-8787-5752
Manuel V Mejía Ramírez-ArellanoServicio de Geriatría, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Rafael Rodríguez-RamosServicio de Inmunología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.
Roberto Pariente-RodríguezServicio de Inmunología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-9323-5236
Luisa M VillarServicio de Inmunología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-9067-3668
Primitivo RamosAgencia Madrileña de Atención Social, 28036 Madrid, Spain.
Rafael CantónServicio de Microbiología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0003-1675-3173
Alfonso J Cruz-JentoftServicio de Geriatría, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-7628-4861
Juan Carlos GalánServicio de Microbiología, Hospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-8447-0960
Instituto Ramón y Cajal de Investigación Sanitaria · ESInstituto de Salud Carlos III · ESAgencia de Evaluación de Tecnologías Sanitarias · ESCentro de Estudios y Experimentación de Obras Públicas · ESHospital Clínico San Carlos · ES

Funding

JYLAG Foundation 2020/154
6 · The paper itself

Abstract

Persons living or working in nursing homes faced a higher risk of SARS-CoV-2 infections during the pandemic, resulting in heightened morbidity and mortality among older adults despite robust vaccination efforts. This prospective study evaluated the humoral and cellular immunity in fully vaccinated residents and workers from two nursing homes in Madrid, Spain, from 2020 to 2021. Measurements of IgG levels were conducted in August 2020 (pre-vaccination) and June and September 2021 (post-vaccination), alongside assessments of neutralizing antibodies and cellular responses in September 2021 among the most vulnerable individuals. Follow-up extended until February 2022 to identify risk factors for SARS-CoV-2 infection or mortality, involving 267 residents (mean age 87.6 years, 81.3% women) and 302 workers (mean age 50.7 years, 82.1% women). Residents exhibited a significantly higher likelihood of experiencing COVID-19 before June 2021 compared with nursing staff (OR [95% CI], 7.2 [3.0 to 17.2],

Indexed as

COVID-19AgedAged, 80 and overAntibodies, NeutralizingAntibodies, ViralFemaleHumansImmunoglobulin GMaleMiddle AgedNursing HomesProspective StudiesRisk FactorsSARS-CoV-2VaccinationAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GCOVID-19immunitynursing homesvaccination

Identifiers

PMID38399962
PMCPMC10891794
OpenAlexW4391219449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.