Evidence map›Paper›PMID 38399768›Full record

ArticleMicroorganisms2024

Seroprevalence of the Hepatitis E Virus in Indigenous and Non-Indigenous Communities from the Brazilian Amazon Basin.

Mariana Pinheiro Alves Vasconcelos, Jaqueline Mendes de Oliveira, Juan Camilo Sánchez-Arcila, Sarah Castro Faria, Moreno Magalhães Rodrigues, Daiana Perce-da-Silva, Joffre Rezende-Neto, Marcelo Alves Pinto, Marilza Maia-Herzog, Dalma Maria Banic and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mariana Pinheiro Alves VasconcelosLaboratório de Imunoparasitologia, Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.ORCID 0000-0001-7211-6887
Jaqueline Mendes de OliveiraLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21045-900, Brazil.ORCID 0000-0002-6759-4574
Juan Camilo Sánchez-ArcilaLaboratório de Imunoparasitologia, Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.ORCID 0000-0002-6879-4439
Sarah Castro FariaLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21045-900, Brazil.
Moreno Magalhães RodriguesFundação Oswaldo Cruz-FIOCRUZ, Porto Velho 76812-245, Brazil.ORCID 0000-0002-1594-2311
Daiana Perce-da-SilvaLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.
Joffre Rezende-NetoInstituto Joffre Rezende, Goiânia 74085-100, Brazil.
Marcelo Alves PintoLaboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21045-900, Brazil.ORCID 0000-0003-3462-7277
Marilza Maia-HerzogLaboratório de Referência Nacional em Simulídeos, Oncocercose e Mansonelose, Coleção de Simulídeos do Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.
Dalma Maria BanicLaboratório de Imunologia Clínica, Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.
Joseli Oliveira-FerreiraLaboratório de Imunoparasitologia, Instituto Oswaldo Cruz-FIOCRUZ/IOC, Rio de Janeiro 21045-900, Brazil.ORCID 0000-0002-6063-465X
Fundação Oswaldo Cruz · BRUniversidade Federal de Rondônia · BR

Funding

Fiocruz Pasteur Program 2013/2015Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/200.938/2022Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.133/2019Fundação Oswaldo Cruz IOC-008-FIO-22-2-49National Council for Scientific and Technological Development 308424/2022-0National Council for Scientific and Technological Development 479559/2013
6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is a common cause of acute viral hepatitis in tropical regions. In Brazil, HEV G3 is the only genotype detected to date. Reports on HEV prevalence are heterogeneous. We aimed to compare the prevalence of anti-HEV among three populations living in the Brazilian Amazon basin. Two cross-sectional studies were conducted in urban, rural, and Yanomami indigenous areas. Plasma samples from 428 indigenous and 383 non-indigenous subjects were tested for anti-HEV IgG using enzyme-linked immunosorbent assays. The overall prevalence of anti-HEV was 6.8% (95%CI: 5.25-8.72), with 2.8% (12/428) found in the Yanomami areas, 3% (3/101) in an urban area, and 14.2% (40/282) in a rural area. Multivariate logistic analysis indicated that patients aged 31-45 years or ≥46 years are more likely to present anti-HEV positivity, with a respective aOR of 2.76 (95%CI: 1.09-7.5) and 4.27 (95%CI: 1.58-12.35). Furthermore, residence in a rural area (aOR: 7.67; 95%CI: 2.50-33.67) represents a relevant risk factor for HEV infection. Additional studies detecting HEV RNA in fecal samples from both humans and potential animal reservoirs are necessary to comprehensively identify risk factors associated with HEV exposure.

Indexed as

Brazilian Amazon RegionBrazilian North Regionhepatitis E seroprevalencehepatitis E virus antibodies (anti-HEV)hepatitis E virus (HEV)indigenous

Identifiers

PMID38399768
PMCPMC10891770
OpenAlexW4391747093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.