Evidence map›Paper›PMID 38399657›Full record

ArticleMicroorganisms2024

The Citizen Phage Library: Rapid Isolation of Phages for the Treatment of Antibiotic Resistant Infections in the UK.

Julie Fletcher, Robyn Manley, Christian Fitch, Christina Bugert, Karen Moore, Audrey Farbos, Michelle Michelsen, Shayma Alathari, Nicola Senior, Alice Mills and 4 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Eliminating the type I restriction endonuclease fromMicrobiology (Reading, England) · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Julie FletcherBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0001-7403-8704
Robyn ManleyBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0002-5152-4504
Christian FitchBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0009-0005-6036-6092
Christina BugertBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Karen MooreBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0002-0146-0653
Audrey FarbosBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Michelle MichelsenBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Shayma AlathariBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0003-2745-3045
Nicola SeniorBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0001-6582-5589
Alice MillsExeter Science Centre, Kaleider Studios, 45 Preston Street, Exeter EX1 1DF, UK.
Natalie WhiteheadExeter Science Centre, Kaleider Studios, 45 Preston Street, Exeter EX1 1DF, UK.ORCID 0000-0002-9174-7286
James SoothillMicrobiology, Virology and Infection Control, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK.
Stephen MichellBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0002-1413-4961
Ben TempertonBiosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.ORCID 0000-0002-3667-8302
University of Exeter · GBExeter Hospital · GBGreat Ormond Street Hospital · GB

Funding

Medical Research Council Confidence in ConceptMedical Research Council MC_PC_19037Medical Research Council MR/N0137941/1Wellcome TrustWellcome Trust 218247/Z/19/Z
6 · The paper itself

Abstract

Antimicrobial resistance poses one of the greatest threats to global health and there is an urgent need for new therapeutic options. Phages are viruses that infect and kill bacteria and phage therapy could provide a valuable tool for the treatment of multidrug-resistant infections. In this study, water samples collected by citizen scientists as part of the Citizen Phage Library (CPL) project, and wastewater samples from the Environment Agency yielded phages with activity against clinical strains

Indexed as

antimicrobial resistancecitizen sciencenamed-patient phage therapyphage cocktailsphage therapy

Identifiers

PMID38399657
PMCPMC10893117
OpenAlexW4391230810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.