Evidence map›Paper›PMID 38399636›Full record

ArticleMicroorganisms2024

Novel Wild-Type

Paraskevi Somalou, Eleftheria Ieronymaki, Kyriaki Feidaki, Ioanna Prapa, Electra Stylianopoulou, Katerina Spyridopoulou, George Skavdis, Maria E Grigoriou, Panayiotis Panas, Anagnostis Argiriou and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Genomic characterization ofApplied and environmental microbiology · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Paraskevi SomalouDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Eleftheria IeronymakiLaboratory of Clinical Chemistry, Department of Laboratory Medicine, Medical School, University of Crete, 71003 Crete, Greece.ORCID 0000-0002-8441-298X
Kyriaki FeidakiInstitute of Applied Sciences, Centre for Research and Technology, 57001 Thessaloniki, Greece.
Ioanna PrapaDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-0280-4443
Electra StylianopoulouDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Katerina SpyridopoulouDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-4905-9567
George SkavdisDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-8929-6431
Maria E GrigoriouDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-6336-5523
Panayiotis PanasQLC, 26442 Patras, Greece.
Anagnostis ArgiriouInstitute of Applied Sciences, Centre for Research and Technology, 57001 Thessaloniki, Greece.ORCID 0000-0002-9164-632X
Christos TsatsanisLaboratory of Clinical Chemistry, Department of Laboratory Medicine, Medical School, University of Crete, 71003 Crete, Greece.ORCID 0000-0003-1214-4151
Yiannis KourkoutasDepartment of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-2842-7666
Democritus University of Thrace · GRCentre for Research and Technology Hellas · GRUniversity of Crete · GR

Funding

European Regional Development Fund of the European Union and Greek national funds Operational Program Competitiveness, Entrepreneurship and Innovation, under the call RESEARCH CREATE- INNOVATE (project: iFUNFoods, code: T1EDK-0346)
6 · The paper itself

Abstract

As the food and pharmaceutical industry is continuously seeking new probiotic strains with unique health properties, the aim of the present study was to determine the impact of short-term dietary intervention with novel wild-type strains, isolated from various sources, on high-fat diet (HFD)-induced insulin resistance. Initially, the strains were evaluated in vitro for their ability to survive in simulated gastrointestinal (GI) conditions, for adhesion to Caco-2 cells, for bile salt hydrolase secretion, for cholesterol-lowering and cellular cholesterol-binding ability, and for growth inhibition of food-borne pathogens. In addition, safety criteria were assessed, including hemolytic activity and susceptibility to antibiotics. The in vivo test on insulin resistance showed that mice receiving the HFD supplemented with

Indexed as

high-fat dietinsulin resistanceLactiplantibacillusobesityPediococcusprobioticstype2 diabetes

Identifiers

PMID38399636
PMCPMC10891751
OpenAlexW4391139824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.