Evidence map›Paper›PMID 38399550›Full record

ReviewMedicina (Kaunas, Lithuania)2024

Updated Strategies in Non-Culprit Stenosis Management of Multivessel Coronary Disease-A Contemporary Review.

Rares-Dumitru Manuca, Alexandra Maria Covic, Crischentian Brinza, Mariana Floria, Cristian Statescu, Adrian Covic, Alexandru Burlacu

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rares-Dumitru ManucaInstitute of Cardiovascular Diseases "Prof. Dr. George I.M. Georgescu", 700503 Iasi, Romania.
Alexandra Maria CovicInstitute of Cardiovascular Diseases "Prof. Dr. George I.M. Georgescu", 700503 Iasi, Romania.
Crischentian BrinzaInstitute of Cardiovascular Diseases "Prof. Dr. George I.M. Georgescu", 700503 Iasi, Romania.ORCID 0000-0002-6253-3203
Mariana FloriaFaculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.ORCID 0000-0002-9465-1503
Cristian StatescuInstitute of Cardiovascular Diseases "Prof. Dr. George I.M. Georgescu", 700503 Iasi, Romania.ORCID 0000-0001-6439-4561
Adrian CovicFaculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.ORCID 0000-0002-9985-2486
Alexandru BurlacuInstitute of Cardiovascular Diseases "Prof. Dr. George I.M. Georgescu", 700503 Iasi, Romania.ORCID 0000-0002-3424-1588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of multivessel coronary artery disease (CAD) in acute coronary syndrome (ACS) patients underscores the need for optimal revascularization strategies. The ongoing debate surrounding percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG), hybrid interventions, or medical-only management adds complexity to decision-making, particularly in specific angiographic scenarios. The article critically reviews existing literature, providing evidence-based perspectives on non-culprit lesion revascularization in ACS. Emphasis is placed on nuances such as the selection of revascularization methods, optimal timing for interventions, and the importance of achieving completeness in revascularization. The debate between culprit-only revascularization and complete revascularization is explored in detail, focusing on ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI), including patients with cardiogenic shock. Myocardial revascularization guidelines and recent clinical trials support complete revascularization strategies, either during the index primary PCI or within a short timeframe following the culprit lesion PCI (in both STEMI and NSTEMI). The article also addresses the complexities of decision-making in NSTEMI patients with multivessel CAD, advocating for immediate multivessel PCI unless complex coronary lesions require a staged revascularization approach. Finally, the article provided contemporary data on chronic total occlusion revascularization in ACS patients, highlighting the prognostic impact. In conclusion, the article addresses the evolving challenges of managing multivessel CAD in ACS patients, enhancing thoughtful integration into the clinical practice of recent data. We provided evidence-based, individualized approaches to optimize short- and long-term outcomes. The ongoing refinement of clinical and interventional strategies for non-culprit lesion management remains dynamic, necessitating careful consideration of patient characteristics, coronary stenosis complexity, and clinical context.

Indexed as

Acute Coronary SyndromeCoronary Artery DiseaseNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionConstriction, PathologicHumansTreatment Outcomeacute coronary syndromecomplete revascularizationmultivessel coronary artery diseasepercutaneous coronary interventionrevascularization strategies

Identifiers

PMID38399550
PMCPMC10890538

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.