Evidence map›Paper›PMID 38399529›Full record

ReviewMedicina (Kaunas, Lithuania)2024

Interleukin-1 Blockers in Recurrent and Acute Pericarditis: State of the Art and Future Directions.

Antonella Gallo, Maria Grazia Massaro, Sara Camilli, Silvino Di Francesco, Laura Gerardino, Elena Verrecchia, Ludovico Luca Sicignano, Francesco Landi, Raffaele Manna, Massimo Montalto

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonella GalloFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5745-7202
Maria Grazia MassaroDepartment of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Sara CamilliDepartment of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Silvino Di FrancescoDepartment of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Laura GerardinoFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.
Elena VerrecchiaFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2131-2110
Ludovico Luca SicignanoFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-4713-0382
Francesco LandiFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.
Raffaele MannaFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0003-1560-3907
Massimo MontaltoFondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.
Università Cattolica del Sacro Cuore · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diseases of the pericardium encompass a spectrum of conditions, including acute and recurrent pericarditis, where inflammation plays a pivotal role in the pathogenesis and clinical manifestations. Anti-inflammatory therapy indeed forms the cornerstone of treating these conditions: NSAIDs, colchicine, and corticosteroids (as a second-line treatment) are recommended by current guidelines. However, these medications come with several contraindications and are not devoid of adverse effects. In recent years, there has been an increased focus on the role of the inflammasome and potential therapeutic targets. Recurrent pericarditis also shares numerous characteristics with other autoinflammatory diseases, in which interleukin-1 antagonists have already been employed with good efficacy and safety. The objective of this review is to summarize the available studies on the use of anti-IL-1 drugs both in acute and recurrent pericarditis.

Indexed as

Interleukin-1PericarditisAdrenal Cortex HormonesAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalHumansRecurrenceAdrenal Cortex HormonesAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalInterleukin-1anti-IL-1 drugsautoinflammatorypericarditis

Identifiers

PMID38399529
PMCPMC10890577
OpenAlexW4391343691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.