Evidence map›Paper›PMID 38399438›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Novel 2,5-Diketopiperazines with In Vitro Activities against Protozoan Parasites of Tropical Diseases.

Isabela P Ceravolo, Letícia F Leoni, Antoniana U Krettli, Silvane M F Murta, Daniela de M Resende, Mariza G F de M L Cruz, Jodieh O S Varejão, Lorena L Mendes, Eduardo V V Varejão, Markus Kohlhoff

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Isabela P CeravoloLaboratory of Immunopathology, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.
Letícia F LeoniLaboratory of Immunopathology, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.
Antoniana U KrettliLaboratory of Immunopathology, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.
Silvane M F MurtaLaboratory of Functional Genomics of Parasites, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.
Daniela de M ResendeLaboratory of Functional Genomics of Parasites, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.ORCID 0000-0002-5139-3022
Mariza G F de M L CruzLaboratory of Functional Genomics of Parasites, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.
Jodieh O S VarejãoLaboratory of Natural Product Chemistry Studies and Organic Synthesis, Federal University of Viçosa (UFV), Av. PH Rolfs, s/n, Viçosa 36570-900, Brazil.
Lorena L MendesLaboratory of Natural Product Chemistry Studies and Organic Synthesis, Federal University of Viçosa (UFV), Av. PH Rolfs, s/n, Viçosa 36570-900, Brazil.
Eduardo V V VarejãoLaboratory of Natural Product Chemistry Studies and Organic Synthesis, Federal University of Viçosa (UFV), Av. PH Rolfs, s/n, Viçosa 36570-900, Brazil.
Markus KohlhoffLaboratory of Bioactive Natural Product Chemistry, René Rachou Institute (IRR), Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715, Belo Horizonte 30190-002, Brazil.ORCID 0000-0001-5982-6083
Fundação Oswaldo Cruz · BRUniversidade Federal de Viçosa · BR

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01577-17Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-02812-21National Council for Scientific and Technological Development 304158/2019-4National Council for Scientific and Technological Development 409751/2018-9National Council for Scientific and Technological Development 438712/2018-8
6 · The paper itself

Abstract

Malaria, Chagas disease, and leishmaniasis are tropical diseases caused by protozoan parasites of the genera

Indexed as

Chagas diseasecyclic dipeptidesdiketopiperazinesLeishmania infantumleishmaniasismalariaPlasmodium falciparumTrypanosoma cruzi

Identifiers

PMID38399438
PMCPMC10893061
OpenAlexW4391654573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.