Evidence map›Paper›PMID 38399422›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

COVID-19 Distribution in Pregnancy, Drug Use Patterns and COVID-19 Medication during the Pandemic in Spain: Data from Real-World Electronic Health Records.

Mercedes Mota-Pérez, Consuelo Huerta-Álvarez, Ana Llorente, Lucía Cea-Soriano

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mercedes Mota-PérezDepartment of Public Health and Maternal Child Health, Faculty of Medicine, Complutense University of Madrid, Plaza Ramón y Cajal, s/n. Ciudad Universitaria, 28040 Madrid, Spain.ORCID 0000-0002-4228-9506
Consuelo Huerta-ÁlvarezDepartment of Public Health and Maternal Child Health, Faculty of Medicine, Complutense University of Madrid, Plaza Ramón y Cajal, s/n. Ciudad Universitaria, 28040 Madrid, Spain.ORCID 0000-0003-4012-7826
Ana LlorenteBase de datos para la Investigación Farmacoepidemiológica en el Ámbito Público (BIFAP), Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency for Medicines and Medical Devices (AEMPS), 28022 Madrid, Spain.
Lucía Cea-SorianoDepartment of Public Health and Maternal Child Health, Faculty of Medicine, Complutense University of Madrid, Plaza Ramón y Cajal, s/n. Ciudad Universitaria, 28040 Madrid, Spain.ORCID 0000-0002-7051-0730

Funding

Instituto de Salud Carlos III Proyectos de Investigación en Salud-Next Generation EU, 2021. Acción Estratégica de Salud 2021-2024. Reference:PI21/00907, entitled: "Historia natural de la infección por SARS-CoV-2 en mujeres gestantes". Mecanismo para la Recuperación y la Resiliencia (M
6 · The paper itself

Abstract

Although pregnant women were considered a risk population for COVID-19, little is known of their drug use during the pandemic. We aimed to investigate COVID-19 distribution, drug use patterns and COVID-19 medication. We conducted a retrospective cohort of validated pregnancies aged 15-49 years, from January 2020 to December 2022, using the BIFAP database. An identified cohort of pregnant women with COVID-19 was matched by age, gestational age, length of pregnancy and outcome to a cohort free of COVID-19 (8413 vs. 24,975). We performed a descriptive analysis on COVID-19 cases, estimated the drug use patterns and assessed COVID-19-specific drugs within the week prior/after diagnosis, stratified by pandemic wave and gestational week. The results showed that 72% of pregnant women with COVID-19 received at least one prescription vs. 66.6% of those free of COVID-19, with analgesics, antibiotics and thyroid hormones being the most prescribed drugs in both groups. In the COVID-19 group, they were antithrombotics (40 prescriptions per 100 women), analgesic/NSAIDs (19.64/6.29) and antibiotics (6.95). COVID-19 cases gradually increased, peaking at the fifth and second waves. Prescription rates were similar when compared to pre-pandemic studies. The use of drugs compatible with COVID-19 treatments was in line with recommendations.

Indexed as

COVID-19drugmedicationpregnancypregnant womenSpain

Identifiers

PMID38399422
PMCPMC10892820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.