Evidence map›Paper›PMID 38399306›Full record

ArticlePharmaceutics2024

Design of Liquid Formulation Based on F127-Loaded Natural Dimeric Flavonoids as a New Perspective Treatment for Leishmaniasis.

Camila Silva da Costa, Estela Mesquita Marques, Jessyane Rodrigues do Nascimento, Victor Antônio Silva Lima, Ralph Santos-Oliveira, Aline Santana Figueredo, Caroline Martins de Jesus, Glécilla Colombelli de Souza Nunes, Clenilma Marques Brandão, Edson Tobias de Jesus and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Therapeutic Potential ofACS omega · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Camila Silva da CostaLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Estela Mesquita MarquesLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Jessyane Rodrigues do NascimentoLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Victor Antônio Silva LimaLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Ralph Santos-OliveiraNuclear Engineering Institute, Brazilian Nuclear Energy Commission, Rio de Janeiro 21941-906, Brazil.ORCID 0000-0002-0905-481X
Aline Santana FigueredoLaboratory of Immunophysiology, Center for Biological and Health Sciences, Federal University of Maranhão, São Luís 65080-805, Brazil.
Caroline Martins de JesusLaboratory of Immunophysiology, Center for Biological and Health Sciences, Federal University of Maranhão, São Luís 65080-805, Brazil.
Glécilla Colombelli de Souza NunesResearch Nucleus in Pharmaceutical Sciences Program, State University of Maringá, Maringá 87020-900, Brazil.
Clenilma Marques BrandãoDepartment of Chemistry, Federal Institute of Maranhão, São Luis 65075-441, Brazil.
Edson Tobias de JesusDepartment of Chemistry, Federal Institute of Maranhão, São Luis 65075-441, Brazil.ORCID 0000-0002-8969-9510
Mayara Coelho SaDepartment of Chemistry, Federal Institute of Maranhão, São Luis 65075-441, Brazil.
Auro Atsushi TanakaDepartment of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0003-4386-4071
Gustavo BragaDepartment of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0001-6383-2152
Ana Caroline Ferreira SantosDepartment of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Roberto Batista de LimaDepartment of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.
Lucilene Amorim SilvaLaboratory of Immunophysiology, Center for Biological and Health Sciences, Federal University of Maranhão, São Luís 65080-805, Brazil.
Luciana Magalhães Rebelo AlencarLaboratory of Biophysics and Nanosystems, Department of Physics, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0001-8210-2016
Cláudia Quintino da RochaLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0002-3578-1869
Renato Sonchini GonçalvesLaboratory of Chemistry of Natural Products, Department of Chemistry, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0003-2701-6101
Universidade Federal do Maranhão · BRInstituto Federal do Maranhão · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious and Parasitic Diseases (IPD) remain a challenge for medicine due to several interconnected reasons, such as antimicrobial resistance (AMR). American tegumentary leishmaniasis (ATL) is an overlooked IPD causing persistent skin ulcers that are challenging to heal, resulting in disfiguring scars. Moreover, it has the potential to extend from the skin to the mucous membranes of the nose, mouth, and throat in both humans and various animals. Given the limited effectiveness and AMR of current drugs, the exploration of new substances has emerged as a promising alternative for ATL treatment.

Indexed as

Arrabidaea brachypodaleishmaniasispluronic F127

Identifiers

PMID38399306
PMCPMC10891960
OpenAlexW4391693298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.