Evidence map›Paper›PMID 38399008›Full record

ArticleMicromachines2024

Using Compound Neural Action Potentials for Functional Validation of a High-Density Intraneural Interface: A Preliminary Study.

Aritra Kundu, Erin Patrick, Seth Currlin, Ryan Madler, Francisco Delgado, Ahmed Fahmy, Rik Verplancke, Marco Ballini, Dries Braeken, Maaike Op de Beeck and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Aritra KunduDepartment of Bioengineering, Imperial College London, SW7 2AZ London, UK.ORCID 0000-0003-2973-3577
Erin PatrickDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2946-7109
Seth CurrlinDepartment of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.
Ryan MadlerDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA.
Francisco DelgadoDepartment of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.
Ahmed FahmyDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA.
Rik VerplanckeCentre for Microsystems Technology (CMST), IMEC and Ghent University, 9052 Zwijnaarde, Belgium.ORCID 0000-0002-6642-9454
Marco BalliniTDK InvenSense, 20057 Milan, Italy.ORCID 0000-0001-7442-8497
Dries BraekenIMEC, Kapeldreef 75, 3001 Leuven, Belgium.ORCID 0000-0002-5752-3203
Maaike Op de BeeckCentre for Microsystems Technology (CMST), IMEC and Ghent University, 9052 Zwijnaarde, Belgium.
Nima MaghariDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA.
Kevin J OttoDepartment of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-2317-6194
Rizwan BashirullahDepartment of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA.
University of Florida · USGhent University · BEIMEC · BE

Funding

Defense Advanced Research Projects Agency N66001-15-C-4018
6 · The paper itself

Abstract

Compound nerve action potentials (CNAPs) were used as a metric to assess the stimulation performance of a novel high-density, transverse, intrafascicular electrode in rat models. We show characteristic CNAPs recorded from distally implanted cuff electrodes. Evaluation of the CNAPs as a function of stimulus current and calculation of recruitment plots were used to obtain a qualitative approximation of the neural interface's placement and orientation inside the nerve. This method avoids elaborate surgeries required for the implantation of EMG electrodes and thus minimizes surgical complications and may accelerate the healing process of the implanted subject.

Indexed as

compound nerve action potentialsintrafascicular electrodesperipheral nerverat model

Identifiers

PMID38399008
PMCPMC10891740
OpenAlexW4391925969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.