Evidence map›Paper›PMID 38398870›Full record

ReviewNutrients2024

The Anti-Inflammatory and Curative Exponent of Probiotics: A Comprehensive and Authentic Ingredient for the Sustained Functioning of Major Human Organs.

Muhammad Safiullah Virk, Muhammad Abdulrehman Virk, Yufeng He, Tabussam Tufail, Mehak Gul, Abdul Qayum, Abdur Rehman, Arif Rashid, John-Nelson Ekumah, Xu Han and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
37.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Pooled it
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  4. The impact ofFrontiers in cellular and infection microbiology · 2025
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  16. Antioxidant and Anti-Inflammatory Activities of Probiotic Strains.International journal of molecular sciences · 2026
    Review
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Muhammad Safiullah VirkSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Muhammad Abdulrehman VirkDepartment of Internal Medicine, Sheikh Zayed Hospital, Lahore 54000, Pakistan.
Yufeng HeSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Tabussam TufailSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-7632-5261
Mehak GulDepartment of Internal Medicine, Sheikh Zayed Hospital, Lahore 54000, Pakistan.
Abdul QayumSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Abdur RehmanSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Arif RashidSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-3976-2956
John-Nelson EkumahSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-1150-8067
Xu HanSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Junxia WangSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Xiaofeng RenSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Jiangsu University · CNShaikh Zayed Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several billion microorganisms reside in the gastrointestinal lumen, including viruses, bacteria, fungi, and yeast. Among them, probiotics were primarily used to cure digestive disorders such as intestinal infections and diarrhea; however, with a paradigm shift towards alleviating health through food, their importance is large. Moreover, recent studies have changed the perspective that probiotics prevent numerous ailments in the major organs. Probiotics primarily produce biologically active compounds targeting discommodious pathogens. This review demonstrates the implications of using probiotics from different genres to prevent and alleviate ailments in the primary human organs. The findings reveal that probiotics immediately activate anti-inflammatory mechanisms by producing anti-inflammatory cytokines such as interleukin (IL)-4, IL-10, IL-11, and IL-13, and hindering pro-inflammatory cytokines such as IL-1, IL-6, and TNF-α by involving regulatory T cells (Tregs) and T helper cells (Th cells). Several strains of

Indexed as

Lacticaseibacillus caseiProbioticsAnti-Inflammatory AgentsCytokinesHumansLactobacillusAnti-Inflammatory AgentsCytokinesBifidobacteriumgut microflorainflammationlactic acid bacteriaLactobacillusprobiotics

Identifiers

PMID38398870
PMCPMC10893534
OpenAlexW4391883395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.