Evidence map›Paper›PMID 38398685›Full record

ArticleLife (Basel, Switzerland)2024

Longitudinal Changes of Cornea Volume Measured by Means of Anterior Segment-Optical Coherence Tomography in Patients with Stable and Progressive Keratoconus.

Sabrina Vaccaro, Chiara Vivarelli, Angeli Christy Yu, Nicolò Pecora, Giovanna Lionetti, Raffaella Gioia, Vincenzo Scorcia, Giuseppe Giannaccare

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sabrina VaccaroDepartment of Ophthalmology, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.
Chiara VivarelliDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Angeli Christy YuDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Nicolò PecoraDepartment of Ophthalmology, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.
Giovanna LionettiDepartment of Ophthalmology, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.
Raffaella GioiaDepartment of Ophthalmology, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Græcia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, Via Università 40, 09124 Cagliari, Italy.ORCID 0000-0003-2617-0289
Magna Graecia University · ITUniversity of Ferrara · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratoconus is a corneal disease which results in progressive thinning and protrusion of the cornea leading to irregular astigmatism. The purpose of this study was to evaluate longitudinal changes in corneal volume (CV) occurring over time in keratoconus eyes. Consecutive patients affected by keratoconus were evaluated by means of anterior segment-optical coherence tomography (AS-OCT) at two different time points: baseline (T0) and after 1 year (T1). Anterior and posterior refractive value; corneal thickness at the thinnest point (TP) and corneal volume (CV) calculated within discs of 3, 5 and 8 mm of diameter; anterior chamber depth (ACD); and anterior chamber volume (ACV) were obtained. Enrolled patients were divided into 3 groups (groups 1, 2, 3) according to the increasing disease severity and into 2 groups (groups A, B) according to the progression or stability of the disease. Overall, 116 eyes of 116 patients (76 males and 40 females, mean age 34.76 ± 13.99 years) were included. For the entire group of keratoconus patients, in comparison with T0, mean TP decreased at T1 from 458.7 ± 52.2 µm to 454.6 ± 51.6 µm (

Indexed as

AS-OCTcorneacorneal thicknesscorneal volumekeratoconus

Identifiers

PMID38398685
PMCPMC10890364
OpenAlexW4391224587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.