Evidence map›Paper›PMID 38398601›Full record

ArticleMolecules (Basel, Switzerland)2024

Chemical Composition Antioxidant and Anti-Inflammatory Activities of

Samia Belahcene, Widad Kebsa, Tomilola Victor Akingbade, Haruna Isiyaku Umar, Damilola Alex Omoboyowa, Abdulaziz A Alshihri, Adel Abo Mansour, Abdulaziz Hassan Alhasaniah, Mohammed A Oraig, Youssef Bakkour and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Samia BelahceneLaboratory of Biotechnology, Environment and Health, Faculty of Nature and Life Sciences, University of Jijel, Jijel 18000, Algeria.ORCID 0009-0001-7657-2537
Widad KebsaLaboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, Jijel 18000, Algeria.
Tomilola Victor AkingbadeComputer-Aided Therapeutic Discovery and Design Platform, Federal University of Technology, PMB 704 Akure, Gaga 340110, Nigeria.ORCID 0009-0004-3295-8851
Haruna Isiyaku UmarComputer-Aided Therapeutic Discovery and Design Platform, Federal University of Technology, PMB 704 Akure, Gaga 340110, Nigeria.
Damilola Alex OmoboyowaPhyto-Medicine and Computational Biology Laboratory, Department of Biochemistry, Adekunle Ajasin University, Akungba Akoko 57257, Nigeria.ORCID 0000-0002-1740-9764
Abdulaziz A AlshihriDepartment of Radiological Sciences, College of Applied Medical Science, King Khalid University, Abha 61421, Saudi Arabia.
Adel Abo MansourDepartment of Clinical Laboratory Sciences, College of Applied Sciences, King Khalid University, Abha 61421, Saudi Arabia.
Abdulaziz Hassan AlhasaniahDepartment of Clinical Laboratory Sciences, College of Applied Sciences, Najran University, Najran 1988, Saudi Arabia.
Mohammed A OraigRadiology Department, Khamis Mushayt General Hospital, Khamis Mushayt 62433, Saudi Arabia.
Youssef BakkourDepartment of Radiological Sciences, College of Applied Medical Science, King Khalid University, Abha 61421, Saudi Arabia.
Essaid LeghouchiLaboratory of Biotechnology, Environment and Health, Faculty of Nature and Life Sciences, University of Jijel, Jijel 18000, Algeria.
King Khalid University · SAUniversity of Jijel · DZFederal University of Technology · NGAdekunle Ajasin University · NGNajran University · SA

Funding

King Khalid University RGP2/454/44
6 · The paper itself

Abstract

Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. In this study, we aimed to systematically unravel the chemical profile and antioxidant and anti-inflammatory activities of myrtle methanolic extract (MMEx) using in vitro, in vivo, and in silico approaches. High levels of TPC (415.85 ± 15.52 mg GAE/g) and TFC (285.80 ± 1.64 mg QE/g) were observed. Mass spectrophotometry (GC-MS) analysis revealed the presence of 1,8-cineole (33.80%), α-pinene (10.06%), linalool (4.83%), p-dimethylaminobenzophenone (4.21%), thunbergol (4%), terpineol (3.60%), cis-geranyl acetate (3.25%), and totarol (3.30%) as major compounds. MMEx induced pronounced dose-dependent inhibition in all assays, and the best antioxidant activity was found with H

Indexed as

AbietanesAntioxidantsMyrtusAnti-Inflammatory AgentsHumansHydrogen PeroxideMolecular Docking SimulationPlant ExtractsAbietanesAnti-Inflammatory AgentsAntioxidantsHydrogen PeroxidePlant ExtractstotarolADMETanti-inflammatoryantioxidantbioactive moleculesmethanolic extractmolecular dockingMyrtus communis L.

Identifiers

PMID38398601
PMCPMC10893115
OpenAlexW4391811417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.