Evidence map›Paper›PMID 38398517›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis and Characterization of Short α and β-Mixed Peptides with Excellent Anti-Lipase Activities.

Naeem Ahmed, Sabahat Asif, Muhammad Arfan, Qaiser Mahmood, Amjad Islam, Mansour K Gatasheh, Muhammad Zia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Naeem AhmedDepartment of Chemistry, School of Natural Sciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.
Sabahat AsifDepartment of Chemistry and Chemical Engineering, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), Lahore 54792, Pakistan.
Muhammad ArfanDepartment of Chemistry, School of Natural Sciences, National University of Sciences and Technology, Islamabad 44000, Pakistan.
Qaiser MahmoodChemistry and Chemical Engineering Guangdong Laboratory, Shantou 515031, China.
Amjad IslamKey Laboratory for Preparation and Application of Ordered Structured Materials of Guangdong Province, College of Chemistry and Chemical Engineering, Shantou University, Shantou 515063, China.ORCID 0000-0002-6094-4682
Mansour K GatashehDepartment of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0101-1014
Muhammad ZiaDepartment of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
National University of Sciences and Technology · PKJi Hua Laboratory · CNKing Saud University · SALahore University of Management Sciences · PKQuaid-i-Azam University · PKShantou University · CN

Funding

Amjad Islam 0bb1baa309ebdbb0,6a5aa5d7ed313e53,61843063f3444df7,58875d947b81e726,615b239e803be0b0,45e50be7ef0245f1,c5d9a4fe383b609e,0ceab0ce3ca2061eKing Saud University RSP2024R393Qaiser Mahmood 9ebfe58b5d63cfdf,0fc4036025155e1a,3a852f3e85a2433b,ffc04817768e29d8,1eae9545a3244bed,db5d8742b53a782c,fc9of098bf237c77,8ce5883758852285
6 · The paper itself

Abstract

Obesity is a source of significant pathologies and deadly diseases, including heart disease, diabetes, and cancer. One of the most intriguing strategies in the hunt for new anti-obesity medications is the inhibition of pancreatic lipase (PL). This study presents a novel application of short α and β-mixed peptides as pancreatic lipase inhibitors. These peptides were synthesized in the solution phase and characterized using FTIR and

Indexed as

PeptidesProlineAmino AcidsHumansLipaseObesityAmino AcidsLipasePeptidesProlineArndt–Eistert methodlipaseobesityWolff rearrangementα and β-hybrid/mixed peptidesβ-amino acid

Identifiers

PMID38398517
PMCPMC10892623
OpenAlexW4391614547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.