Evidence map›Paper›PMID 38398226›Full record

ArticleCancers2024

Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses.

Muhamad Serhal, Sean Rangwani, Stephen M Seedial, Bartley Thornburg, Ahsun Riaz, Albert A Nemcek, Kent T Sato, Kent T Perry, Bonnie Choy, Robert J Lewandowski and 1 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Muhamad SerhalSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Sean RangwaniNorthwestern University Feinberg School of Medicine, Chicago Campus, Chicago, IL 60611, USA.
Stephen M SeedialSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Bartley ThornburgSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Ahsun RiazSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Albert A NemcekSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Kent T SatoSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Kent T PerryDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Bonnie ChoyDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-3670-3715
Robert J LewandowskiSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-5510-788X
Andrew C GordonSection of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-0092-249X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImage-guided renal mass biopsy is gaining increased diagnostic acceptance, but there are limited data concerning the safety and diagnostic yield of biopsy for small renal masses (≤4 cm). This study evaluated the safety, diagnostic yield, and management after image-guided percutaneous biopsy for small renal masses.

methodsA retrospective IRB-approved study was conducted on patients who underwent renal mass biopsy for histopathologic diagnosis at a single center from 2015 to 2021. Patients with a prior history of malignancy or a renal mass >4 cm were excluded. Descriptive statistics were used to summarize patient demographics, tumor size, the imaging modality used for biopsy, procedure details, complications, pathological diagnosis, and post-biopsy management. A biopsy was considered successful when the specimen was sufficient for diagnosis without need for a repeat biopsy. Complications were graded according to the SIR classification of adverse events. A chi-squared test (significance level set at

resultsA total of 167 patients met the inclusion criteria. The median age was 65 years (range: 26-87) and 51% were male. The median renal mass size was 2.6 cm (range: one-four). Ultrasound was solely employed in 60% of procedures, CT in 33%, a combination of US/CT in 6%, and MRI in one case. With on-site cytopathology, the median number of specimens obtained per procedure was four (range: one-nine). The overall complication rate was 5%. Grade A complications were seen in 4% (

conclusionThis study demonstrates the safety and diagnostic efficacy of image-guided biopsy of small renal masses. The diagnostic yield was significantly higher for masses 3-4 cm in size compared to those <3 cm. The biopsy results showed a high percentage of benign diagnoses and informed treatment decisions in most patients.

Indexed as

biopsycomplicationimage-guidedkidney neoplasms

Identifiers

PMID38398226
PMCPMC10887197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.