Evidence map›Paper›PMID 38398207›Full record

ArticleCancers2024

Relationship between the Expression of CHK2 and p53 in Tumor Tissue and the Course of Papillary Thyroid Cancer in Patients with

Danuta Gąsior-Perczak, Artur Kowalik, Janusz Kopczyński, Paweł Macek, Kornelia Niemyska, Agnieszka Walczyk, Krzysztof Gruszczyński, Monika Siołek, Tomasz Dróżdż, Marcin Kosowski and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. p53 prophylactic therapy for cancer prevention.Cell death and differentiation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Danuta Gąsior-PerczakCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0003-0936-4890
Artur KowalikDepartment of Molecular Diagnostics, Holycross Cancer Centre, S. Artwińskiego Str. 3, 25-734 Kielce, Poland.ORCID 0000-0002-3718-999X
Janusz KopczyńskiSurgical Pathology, Holycross Cancer Centre, S. Artwińskiego Str. 3, 25-734 Kielce, Poland.
Paweł MacekCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0001-9755-7507
Kornelia NiemyskaSurgical Pathology, Holycross Cancer Centre, S. Artwińskiego Str. 3, 25-734 Kielce, Poland.
Agnieszka WalczykCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.
Krzysztof GruszczyńskiDepartment of Molecular Diagnostics, Holycross Cancer Centre, S. Artwińskiego Str. 3, 25-734 Kielce, Poland.
Monika SiołekGenetic Clinic, Holycross Cancer Centre, 25-734 Kielce, Poland.
Tomasz DróżdżCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.
Marcin KosowskiCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.
Iwona PałygaCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.
Piotr PrzybycieńEndocrinology Clinic, Holycross Cancer Centre, S. Artwińskiego St. 3, 25-734 Kielce, Poland.
Olga WabikSurgical Pathology, Holycross Cancer Centre, S. Artwińskiego Str. 3, 25-734 Kielce, Poland.
Stanisław GóźdźCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.
Aldona KowalskaCollegium Medicum, Jan Kochanowski University, 25-317 Kielce, Poland.ORCID 0000-0001-5647-5898
Jan Kochanowski University · PLHoly Cross University · PL

Funding

Regional Initiative of Excellence 024/RID/2018/19
6 · The paper itself

Abstract

The aim of this study was to determine whether the expression of CHK2 and p53 in tumor tissue in carriers of germline

Indexed as

checkpoint kinase 2CHEK2 mutationfluorescence in situ hybridizationimmunohistochemistryp53papillary thyroid cancerTP53 gene

Identifiers

PMID38398207
PMCPMC10886656
OpenAlexW4391986395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.