Evidence map›Paper›PMID 38398132›Full record

ArticleCancers2024

Functional Homologous Recombination (HR) Screening Shows the Majority of

Titia G Meijer, John W M Martens, Wendy J C Prager-van der Smissen, Nicole S Verkaik, Corine M Beaufort, Stanley van Herk, Teresa Robert-Finestra, Remco M Hoogenboezem, Kirsten Ruigrok-Ritstier, Maarten W Paul and 6 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Dual Targeting of CXCancers · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Titia G MeijerDepartment of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
John W M MartensDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-3428-3366
Wendy J C Prager-van der SmissenDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Nicole S VerkaikDepartment of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Corine M BeaufortDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Stanley van HerkOncode Institute, 3521 AL Utrecht, The Netherlands.
Teresa Robert-FinestraOncode Institute, 3521 AL Utrecht, The Netherlands.ORCID 0000-0003-0220-8748
Remco M HoogenboezemDepartment of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Kirsten Ruigrok-RitstierDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Maarten W PaulDepartment of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-7990-6010
Joost GribnauOncode Institute, 3521 AL Utrecht, The Netherlands.
Eric M J BindelsDepartment of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-9502-669X
Roland KanaarDepartment of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Agnes JagerDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Dik C van GentDepartment of Molecular Genetics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1473-8148
Antoinette HollestelleDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1166-1966

Funding

Dutch Cancer Society EMCR 2008-4045Dutch Cancer Society EMCR 2014-7048
6 · The paper itself

Abstract

Tumors with a pathogenic

Indexed as

BRCA1/2breast cancercell linesfunctional statushomologous recombination repairmutational signaturemutation statusovarian cancer

Identifiers

PMID38398132
PMCPMC10887177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.