Evidence map›Paper›PMID 38398130›Full record

ReviewCancers2024

Management of Intrahepatic Cholangiocarcinoma: A Narrative Review.

Carolyn Tsung, Patrick L Quinn, Aslam Ejaz

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  7. Article
  8. Organoids and spheroids: advancedFrontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Carolyn TsungDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Patrick L QuinnDepartment of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Aslam EjazDepartment of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA.
The Ohio State University Wexner Medical Center · USUniversity of Illinois Chicago · US

Funding

ACCELERATE: Accelerating HSR at OSUT32HS029590 · AHRQ · OHIO STATE UNIVERSITY · PI BURKE, JAMES FRANCIS, JONAS, DANIEL E · 2023 to 2024
$695k
AHRQ HHS T32 HS029590
6 · The paper itself

Abstract

The management of resectable intrahepatic cholangiocarcinoma remains a challenge due to the high risk of recurrence. Numerous clinical trials have identified effective systemic therapies for advanced biliary tract cancer; however, fewer trials have evaluated systemic therapies in the perioperative period. The objective of this review is to summarize the current recommendations regarding the diagnosis, surgical resection, and systemic therapy for anatomically resectable intrahepatic cholangiocarcinoma. Our review demonstrates that surgical resection with microscopic negative margins and lymphadenectomy remains the cornerstone of treatment. High-level evidence regarding specific systemic therapies for use in resectable intrahepatic cholangiocarcinoma remains sparse, as most of the evidence is extrapolated from trials involving heterogeneous tumor populations. Targeted therapies are an evolving practice for intrahepatic cholangiocarcinoma with most evidence coming from phase II trials. Future research is required to evaluate the use of neoadjuvant therapy for patients with resectable and borderline resectable disease.

Indexed as

adjuvantimmunotherapyintrahepatic cholangiocarcinomaprecision medicinesystemic therapytargeted therapy

Identifiers

PMID38398130
PMCPMC10886475
OpenAlexW4391753145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.