Evidence map›Paper›PMID 38398126›Full record

ArticleCancers2024

The C250T Mutation of

Teresa Gorria, Carme Crous, Estela Pineda, Ainhoa Hernandez, Marta Domenech, Carolina Sanz, Pedro Jares, Ana María Muñoz-Mármol, Oriol Arpí-Llucía, Bárbara Melendez and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 1 country.

Teresa GorriaMedical Oncology, Hospital Clínic, Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Carme CrousMedical Oncology, Hospital Clínic, Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Estela PinedaMedical Oncology, Hospital Clínic, Translational Genomics and Targeted Therapeutics in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0003-2128-747X
Ainhoa HernandezMedical Oncology, Institut Catala d'Oncologia (ICO) Badalona, Badalona Applied Research Group in Oncology (B-ARGO Group), Institut Investigació Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.
Marta DomenechMedical Oncology, Institut Catala d'Oncologia (ICO) Badalona, Badalona Applied Research Group in Oncology (B-ARGO Group), Institut Investigació Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.ORCID 0000-0003-4827-9170
Carolina SanzPathology Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain.
Pedro JaresDepartment of Pathology, Biomedical Diagnostic Centre (CDB) and Neurological Tissue Bank of the Biobank-IDIBAPS, Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.
Ana María Muñoz-MármolPathology Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain.
Oriol Arpí-LlucíaCancer Research Program, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), 08003 Barcelona, Spain.
Bárbara MelendezMolecular Pathology Research Unit, Hospital Universitario de Toledo, 45007 Toledo, Spain.
Marta GutCentro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028 Barcelona, Spain.
Anna EsteveMedical Oncology, Institut Catala d'Oncologia (ICO) Badalona, Badalona Applied Research Group in Oncology (B-ARGO Group), Institut Investigació Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.ORCID 0000-0002-1962-971X
Anna Esteve-CodinaCentro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028 Barcelona, Spain.
Genis ParraCentro Nacional de Análisis Genómico, C/Baldiri Reixac 4, 08028 Barcelona, Spain.
Francesc AlamedaPathology Department, Neuropathology Unit, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), 08003 Barcelona, Spain.
Cristina CarratoPathology Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain.
Iban AldecoaDepartment of Pathology, Biomedical Diagnostic Centre (CDB) and Neurological Tissue Bank of the Biobank-IDIBAPS, Hospital Clinic, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-5774-7453
Mar MalloUnidad de Microarrays, Institut de Recerca Contra la Leucèmia Josep Carreras (IJC), ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.ORCID 0000-0001-7741-498X
Nuria de la IglesiaIrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain.ORCID 0000-0002-1083-7715
Carmen BalanaPathology Department, Neuropathology Unit, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), 08003 Barcelona, Spain.
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESCentro Nacional de Análisis Genómico · ESHospital del Mar Research Institute · ESHospital Universitari Germans Trias i Pujol · ESInstitut Català d'Oncologia · ESComplejo Hospitalario Universitario de Toledo · ESIrsiCaixa · ESUniversitat Autònoma de Barcelona · ES

Funding

Fundació La Marató TV3 665/C/2013Instituto de Salud Carlos III PI118/01062
6 · The paper itself

Abstract

The aim of this study was to determine how MATERIALS AND

methods

resultsOverall, there were no differences in outcomes between patients with mutated

conclusionsIn our series, patients exhibiting the C250T mutation had a more favorable prognosis compared to those with either

Indexed as

glioblastomaMGMTp methylationRNA-Seq differential expression analysisTERTp mutationswhole-exome sequencing

Identifiers

PMID38398126
PMCPMC10886885
OpenAlexW4391678752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.