Evidence map›Paper›PMID 38398120›Full record

ArticleCancers2024

LIONS PREY: A New Logistic Scoring System for the Prediction of Malignant Pulmonary Nodules.

Fabian Doerr, Annika Giese, Katja Höpker, Hruy Menghesha, Georg Schlachtenberger, Konstantinos Grapatsas, Natalie Baldes, Christian J Baldus, Lars Hagmeyer, Hazem Fallouh and 11 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Fabian DoerrDepartment of Thoracic Surgery, West German Cancer Center, University Medical Center Essen-Ruhrlandklinik, University Duisburg-Essen, 45239 Essen, Germany.ORCID 0000-0002-0878-0406
Annika GieseDepartment of Anesthesiology and Intensive Care Medicine, Vinzenz Pallotti Hospital Bergisch Gladbach-Bensberg, GFO-Clinics Rhein-Berg, 51429 Bergisch Gladbach, Germany.
Katja HöpkerClinic III for Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50923 Cologne, Germany.
Hruy MengheshaDepartment of Thoracic Surgery, Helios Clinic Bonn/Rhein-Sieg, 53123 Bonn, Germany.
Georg SchlachtenbergerDepartment of Cardiothoracic Surgery, University Hospital of Cologne, University of Cologne, 50923 Cologne, Germany.ORCID 0000-0001-7118-8432
Konstantinos GrapatsasDepartment of Thoracic Surgery, West German Cancer Center, University Medical Center Essen-Ruhrlandklinik, University Duisburg-Essen, 45239 Essen, Germany.
Natalie BaldesDepartment of Thoracic Surgery, West German Cancer Center, University Medical Center Essen-Ruhrlandklinik, University Duisburg-Essen, 45239 Essen, Germany.
Christian J BaldusInstitute for Diagnostic and Interventional Radiology, University Hospital Dresden, 01307 Dresden, Germany.
Lars HagmeyerClinic for Pneumology and Allergology, Bethanien Hospital GmbH Solingen, 42699 Solingen, Germany.
Hazem FallouhDepartment of Cardiothoracic Surgery, University Hospital of Birmingham, Birmingham B15 2GW, UK.
Daniel Pinto Dos SantosDepartment of Radiology, University Hospital Cologne, 50937 Cologne, Germany.ORCID 0000-0003-4785-6394
Edward M BenderDepartment of Cardiothoracic Surgery, Stanford University, Palo Alto, CA 94304, USA.
Alexander QuaasInstitute of Pathology, University of Cologne, 50923 Cologne, Germany.ORCID 0000-0002-3537-6011
Matthias HeldweinDivision of Thoracic Surgery, Department of General, Thoracic and Vascular Surgery, Bonn University Hospital, 53127 Bonn, Germany.
Thorsten WahlersDivision of Thoracic Surgery, Department of General, Thoracic and Vascular Surgery, Bonn University Hospital, 53127 Bonn, Germany.
Hubertus HautzelDepartment of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, 45239 Essen, Germany.
Kaid DarwicheDepartment of Pneumology, West German Cancer Center, University Medical Center Essen-Ruhrlandklinik, University Duisburg-Essen, 45239 Essen, Germany.ORCID 0000-0003-0681-1325
Christian TaubeDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, 45239 Essen, Germany.
Martin SchulerDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, 45239 Essen, Germany.ORCID 0000-0002-2166-3394
Khosro HekmatDivision of Thoracic Surgery, Department of General, Thoracic and Vascular Surgery, Bonn University Hospital, 53127 Bonn, Germany.
Servet BölükbasDepartment of Thoracic Surgery, West German Cancer Center, University Medical Center Essen-Ruhrlandklinik, University Duisburg-Essen, 45239 Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesClassifying radiologic pulmonary lesions as malignant is challenging. Scoring systems like the Mayo model lack precision in predicting the probability of malignancy. We developed the logistic scoring system 'LIONS PREY' (Lung lesION Score PREdicts malignancY), which is superior to existing models in its precision in determining the likelihood of malignancy.

methodsWe evaluated all patients that were presented to our multidisciplinary team between January 2013 and December 2020. Availability of pathological results after resection or CT-/EBUS-guided sampling was mandatory for study inclusion. Two groups were formed: Group A (malignant nodule; n = 238) and Group B (benign nodule; n = 148). Initially, 22 potential score parameters were derived from the patients' medical histories.

resultsAfter uni- and multivariate analysis, we identified the following eight parameters that were integrated into a scoring system: (1) age (Group A: 64.5 ± 10.2 years vs. Group B: 61.6 ± 13.8 years; multivariate

conclusionsFocusing on essential parameters, LIONS PREY can be easily and reproducibly applied based on computed tomography (CT) scans. Multidisciplinary team members could use it to facilitate decision making. Patients may find it easier to consent to surgery knowing the likelihood of pulmonary malignancy. The LIONS PREY app is available for free on Android and iOS devices.

Indexed as

logistic scoring systemmalignancypulmonary lesionsmartphone

Identifiers

PMID38398120
PMCPMC10887049

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.