ArticleBiomedicines2024
Understanding Neuropathy Features in the Context of Nitrous Oxide Abuse: A Combined Electrophysiological and Metabolic Approach.
Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Optic Neuropathy Associated with Recreational Abuse of Nitrous Oxide: A Retrospective Case Series.Journal of clinical medicine · 2026Article
- Article
- Neurological disorders caused by recreational use of nitrous oxide-a retrospective study from a German metropolitan area and review of the literature.Neurological research and practice · 2025Article
- Comparative study of subacute combined degeneration of the spinal cord due to nitrous oxide abuse and vitamin B12 deficiency.Frontiers in immunology · 2025Article
- Factors affecting the topography of nitrous oxide-induced neurological complications.European journal of neurology · 2024Observational
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of neurological complications associated with nitrous oxide (N
methodsWe conducted a combined metabolic and electrophysiological exploration of 35 patients who underwent electromyographic exams at our referral center over a three-year period for sensorimotor symptoms linked to recreational N
resultsOur cohort predominantly exhibited a length-dependent sensorimotor axonal symmetrical neuropathy affecting the lower limbs. Among the patients, 40% met the demyelinating criteria, with four patients exhibiting conduction blocks. The demyelinating group had a significantly higher peripheral neuropathy disability (PND) score at diagnosis. Elevated homocysteine and methylmalonic acid (MMA) levels were noted in all patients, but these were lower in the demyelinating group.
conclusionsThis study highlights the diverse electrophysiological manifestations of N
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Registered trials
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